# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2340615 | B | Selectivity ratio of IC50 for human DHFR to Candida glabrata DHFR | 11 | assay format | Scientific Literature | |||
2. | ALA2340616 | B | Inhibition of human DHFR | Homo sapiens | 11 | single protein format | Scientific Literature | ||
3. | ALA2340617 | B | Selectivity ratio of IC50 for human DHFR to Candida albicans DHFR | 11 | assay format | Scientific Literature | |||
4. | ALA2340618 | B | Inhibition of Candida glabrata DHFR | Nakaseomyces glabratus | 11 | assay format | Scientific Literature | ||
5. | ALA2340620 | B | Inhibition of Candida albicans DHFR | Candida albicans | 11 | single protein format | Scientific Literature | ||
6. | ALA3530563 | B | Inhibition of Staphylococcus aureus DHFR assessed as reduction in rate of NADPH consumption | Staphylococcus aureus | 9 | single protein format | Scientific Literature | ||
7. | ALA3530564 | F | Antimicrobial activity against Staphylococcus aureus | Staphylococcus aureus | 8 | organism-based format | Scientific Literature | ||
8. | ALA3530565 | P | Kinetic solubility of the compound | 6 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA3705794 | B | Enzyme Inhibition Assay: Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureus and S. pyogenes inhibition, and evaluated for mammalian cell toxicity. | Staphylococcus aureus | 15 | single protein format | BindingDB Database | ||
10. | ALA3707851 | B | Enzyme Inhibition Assay: Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureus and S. pyogenes inhibition, and evaluated for mammalian cell toxicity. | Homo sapiens | 15 | single protein format | BindingDB Database | ||
11. | ALA3707492 | B | Enzyme Inhibition Assay: Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureus and S. pyogenes inhibition, and evaluated for mammalian cell toxicity. | 15 | single protein format | BindingDB Database |