# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2341487 | F | Antitumor activity against human BT-483 cells xenografted in nude mouse assessed as decrease in tumor growth at 20 mg/kg/day, ip for 2 weeks measured every 3 days by caliper analysis | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
2. | ALA2341488 | B | Binding affinity to Tubulin alpha/beta in human BT-483 cells assessed as microtubule depolymerization at 1 uM after 6 hrs by immunofluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2341490 | F | Induction of DNA damage in human BT-483 cells assessed as gamma H2AX phosphorylation at Ser139 at 1 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2341492 | F | Induction of apoptosis in human BT-483 cells assessed as PARP cleavage at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA2341493 | F | Induction of apoptosis in human BT-483 cells assessed as increase in caspase 3 activity at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2341494 | F | Cell cycle arrest in human BT-483 cells assessed as accumulation of cells at subG1 phase at 0.2 uM after 24 hrs by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA2341495 | F | Cell cycle arrest in human BT-483 cells assessed as accumulation of cells at G2/M phase at 0.2 uM after 12 hrs by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA2341496 | F | Cytotoxicity against human SKHEP1 cells assessed as growth inhibition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
9. | ALA2341497 | F | Cytotoxicity against human CE81T cells assessed as growth inhibition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
10. | ALA2341498 | F | Cytotoxicity against human SAS cells assessed as growth inhibition | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA2341499 | F | Cytotoxicity against human HeLa cells assessed as growth inhibition | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
12. | ALA2341500 | F | Cytotoxicity against human PC3 cells assessed as growth inhibition | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
13. | ALA2341501 | F | Cytotoxicity against human BT-483 cells assessed as growth inhibition | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
14. | ALA2342013 | F | Cytotoxicity against human AGS cells assessed as growth inhibition | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
15. | ALA2342014 | F | Cytotoxicity against human A549 cells assessed as growth inhibition | Homo sapiens | 11 | cell-based format | Scientific Literature |