# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2344216 | F | Neuroprotective activity in human SH-SY5Y cells assessed as inhibition of paraquat-induced cell death at 10 uM incubated for 2 hrs prior to paraquat challenge measured after 24 hrs by MTT assay (Rvb = 62.05 +/- 0.47%) | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA2412086 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 20 uM treated 2 hrs before LPS challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
3. | ALA2412087 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IL-1beta release at 20 uM after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA2412088 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS expression at 20 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA2412089 | B | Inhibition of LPS-induced ERK1/2 phosphorylation in mouse RAW264.7 cells at 5 to 20 uM after 45 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA2412090 | B | Inhibition of LPS-induced JNK1/2 phosphorylation in mouse RAW264.7 cells after 45 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA2412091 | B | Inhibition of LPS-induced p38 MAPK phosphorylation in mouse RAW264.7 cells after 45 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA2412092 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 2 hrs prior to LPS challenge measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA2412093 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS protein expression incubated for 2 hrs prior to LPS challenge measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA2412094 | A | Cytotoxicity against mouse RAW264.7 cells up to 20 uM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA2412095 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production treated 2 hrs before LPS challenge measured after 24 hrs | Mus musculus | 31 | cell-based format | Scientific Literature | ||
12. | ALA2412096 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 10 uM treated 2 hrs before LPS challenge measured after 24 hrs | Mus musculus | 34 | cell-based format | Scientific Literature |