# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2341133 | F | Ratio of compound IC50 to roscovitine IC50 for human MCF7 cells after 72 hrs by calcien AM dye based fluorescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2341134 | B | Activity at Aurora kinase A/B in human MCF7 cells assessed as histone H3 phosphorylation at Ser10 at 100 uM after 24 hrs by flow cytometry relative to untreated control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
3. | ALA2346094 | B | Ratio of compound IC50 to roscovitine IC50 for recombinant CDK2/cyclin E (unknown origin) | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
4. | ALA2346095 | B | Ratio of compound IC50 to roscovitine IC50 for recombinant CDK1/cyclin B (unknown origin) | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
5. | ALA2346096 | F | Cell cycle arrest in human MCF7 cells assessed as accumulation of cells in G2+M phase at 100 uM after 24 hrs by propidium iodide staining based flow cytometry relative to untreated control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
6. | ALA2346097 | F | Cytotoxicity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by calcien AM dye based fluorescence analysis | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
7. | ALA2346098 | B | Inhibition of recombinant CDK2/cyclin E (unknown origin) using histone H1 as substrate in presence of [gamma-33P]ATP | Homo sapiens | 30 | protein complex format | Scientific Literature | ||
8. | ALA2346099 | B | Inhibition of recombinant CDK1/cyclin B (unknown origin) using histone H1 as substrate in presence of [gamma-33P]ATP | Homo sapiens | 30 | protein complex format | Scientific Literature |