# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2343618 | F | Induction of apoptosis in human HCT116 cells assessed as induction of PARP cleavage by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA2343619 | B | Inhibition of proteasome in human HCT116 cells assessed as accumulation of p53 by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA2343620 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G2/M phase after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA2343621 | F | Cytotoxicity against human HCT116 cells after 72 hrs by CCK-8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA2343626 | B | Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Ac-RLR-AMC as substrate after 60 mins by fluorescence assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
6. | ALA2343627 | B | Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Ac-nLPnLD-AMC as substrate after 60 mins by fluorescence assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
7. | ALA2343628 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assay | Homo sapiens | 28 | single protein format | Scientific Literature |