# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2341952 | Binding | Inhibition of human neutrophil elastase-induced increase in IL8 mRNA levels at 10 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
2. | ALA2341953 | Binding | Inhibition of human neutrophil elastase-induced increase in IL1alpha mRNA levels at 10 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
3. | ALA2341954 | Binding | Inhibition of human neutrophil elastase-induced increase in IL1beta mRNA levels at 10 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
4. | ALA2342448 | Binding | Inhibition of human neutrophil elastase-induced increase in IL8 mRNA levels at 10 uM after 3 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
5. | ALA2342449 | Binding | Inhibition of human neutrophil elastase-induced increase in IL1alpha mRNA levels at 10 uM after 3 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
6. | ALA2342450 | Binding | Inhibition of human neutrophil elastase-induced increase in IL1beta mRNA levels at 10 uM after 3 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
7. | ALA2342451 | Binding | Inhibition of human neutrophil elastase-induced IL8 transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
8. | ALA2342452 | Binding | Inhibition of human neutrophil elastase-induced TAB2 transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
9. | ALA2342453 | Binding | Inhibition of human neutrophil elastase-induced IL1A transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
10. | ALA2342454 | Binding | Inhibition of human neutrophil elastase-induced RAP1A transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
11. | ALA2342455 | Binding | Inhibition of human neutrophil elastase-induced SOS1 transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
12. | ALA2342456 | Binding | Inhibition of human neutrophil elastase-induced NLK transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
13. | ALA2342457 | Binding | Inhibition of human neutrophil elastase-induced IL6 transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
14. | ALA2342458 | Binding | Inhibition of human neutrophil elastase-induced PPP3R1 transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
15. | ALA2342459 | Binding | Inhibition of human neutrophil elastase-induced IL1beta transcript level | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
16. | ALA2342460 | Binding | Inhibition of human neutrophil elastase-induced transcriptional response at 10 uM | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
17. | ALA2342461 | Binding | Inhibition of human neutrophil elastase-induced increase in nuclear translocation of p65 after 3 hrs by Western blotting analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
18. | ALA2342462 | Binding | Inhibition of human neutrophil elastase-induced decrease in IkappaB level after 3 hrs by Western blotting analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
19. | ALA2342463 | Binding | Inhibition of human neutrophil elastase assessed as ICAM1 transcript levels at 10 uM after 3 to 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA2331221 | single protein format | Scientific Literature | |
20. | ALA2342464 | Binding | Inhibition of human neutrophil elastase-induced decrease in mICAM1 level expressed in BEAS2B cells assessed as cytoprotective activity after 6 hrs by Western blotting analysis | Homo sapiens | 2 | ALA2331221 | cell-based format | Scientific Literature |