| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2343129 | F | Cognitive enhancing effect in MK-801-treated ddY mouse assessed as increase in alteration rate at 0.003 to 0.3 mg/kg, po administered 10 mins before MK-801 challenge measured after 20 mins by Y-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2343130 | B | Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA2343131 | B | Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA2343132 | B | Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 5. | ALA2343135 | B | Inhibition of human recombinant DAAO after 30 mins by plate reader analysis | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 6. | ALA2343136 | A | Drug uptake in ddY mouse brain at 30 mg/kg, po after 30 mins by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2343137 | A | Plasma concentration in ddY mouse at 30 mg/kg, po after 30 mins by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2343138 | F | Cognitive enhancing effect in MK-801-treated ddY mouse assessed as total number of arm entries at 0.003 to 0.3 mg/kg, po administered 10 mins before MK-801 challenge measured after 20 mins by Y-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3384562 | A | Drug metabolism in mouse liver microsomes assessed as glucuronidation of compound measured as compound remaining after 30 mins by LC/MS analysis | Mus musculus | 12 | assay format | Scientific Literature | ||
| 10. | ALA3384563 | A | Drug metabolism in rat liver microsomes assessed as glucuronidation of compound measured as compound remaining after 30 mins by LC/MS analysis | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 11. | ALA3384564 | A | Drug metabolism in human liver microsomes assessed as glucuronidation of compound measured as compound remaining after 30 mins by LC/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3384565 | A | Drug metabolism in mouse liver microsomes assessed as glucuronidation of compound measured as compound remaining after 60 mins by LC/MS analysis | Mus musculus | 12 | assay format | Scientific Literature | ||
| 13. | ALA3384566 | A | Drug metabolism in rat liver microsomes assessed as glucuronidation of compound measured as compound remaining after 60 mins by LC/MS analysis | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 14. | ALA3384567 | A | Drug metabolism in human liver microsomes assessed as glucuronidation of compound measured as compound remaining after 60 mins by LC/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3384568 | A | Oral bioavailability in CD1 mouse at 30 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3384569 | A | Plasma clearance in CD1 mouse at 30 mg/kg, po and 10 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3614586 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 5 uM after 60 mins by LC/MS/MS analysis in presence of UDPGA | Mus musculus | 6 | assay format | Scientific Literature | ||
| 18. | ALA3614587 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 5 uM after 60 mins by LC/MS/MS analysis in presence of NADPH | Mus musculus | 6 | assay format | Scientific Literature | ||
| 19. | ALA3614596 | A | Clearance in CD1 mouse at 10 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3614597 | A | Volume of distribution in CD1 mouse at 10 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!