| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2353008 | F | Antiproliferative activity against human T47D cells at 1 to 10 uM after 48 hrs by SRB assay | Homo sapiens | 11 | ALA2346643 | cell-based format | Scientific Literature | |
| 2. | ALA2353009 | F | Antiproliferative activity against human MDA-MB-231 cells at 1 to 10 uM after 48 hrs by SRB assay | Homo sapiens | 11 | ALA2346643 | cell-based format | Scientific Literature | |
| 3. | ALA2353024 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of oxygen consumption at 30 uM after 5 to 10 mins by Clarke-type electrode analysis | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature | |
| 4. | ALA2353250 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature | |
| 5. | ALA2353251 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature | |
| 6. | ALA2353252 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of oxygen consumption after 5 to 10 mins by Clarke-type electrode analysis | Homo sapiens | 7 | ALA2346643 | cell-based format | Scientific Literature | |
| 7. | ALA4154459 | A | Cytotoxicity against mouse Melan-a cells assessed as effect on cell viability at <2 uM after 24 to 72 hrs by trypan blue exclusion assay | Mus musculus | 8 | ALA4152246 | cell-based format | Scientific Literature | |
| 8. | ALA4154460 | F | Induction of melanogenesis in mouse Melan-a cells assessed as effect on tanning property at 40 uM after 48 hrs | Mus musculus | 9 | ALA4152246 | cell-based format | Scientific Literature | |
| 9. | ALA4154461 | F | Inhibition of melanogenesis in mouse Melan-a cells assessed as effect on whitening property at 40 uM after 48 hrs | Mus musculus | 9 | ALA4152246 | cell-based format | Scientific Literature | |
| 10. | ALA5229428 | T | Cytotoxicity against human BMMSC cells assessed as reduction in cell viability at 10 uM incubated for 72 hrs by CCK8 assay | Homo sapiens | 28 | ALA5226363 | cell-based format | Scientific Literature | |
| 11. | ALA5229429 | B | Displacement of fluormone pan-PPARgreen from GST-tagged human PPARalpha ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 2 | ALA5226363 | single protein format | Scientific Literature | |
| 12. | ALA5229430 | B | Displacement of fluormone pan-PPARgreen from GST-tagged human PPARdelta ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 2 | ALA5226363 | single protein format | Scientific Literature | |
| 13. | ALA5229431 | B | Displacement of fluormone pan-PPARgreen from GST-tagged human PPARgamma ligand binding domain at 10 uM by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 2 | ALA5226363 | single protein format | Scientific Literature | |
| 14. | ALA5229432 | B | Agonist activity at GST-tagged LXR-beta ligand binding domain (unknown origin) at 10 uM LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 2 | ALA5226363 | single protein format | Scientific Literature | |
| 15. | ALA5229433 | B | Agonist activity at GST-tagged FXR ligand binding domain (unknown origin) at 10 uM LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 2 | ALA5226363 | single protein format | Scientific Literature | |
| 16. | ALA5229434 | B | Displacement of fluormone pan-PPARgreen from GST-tagged human PPARgamma ligand binding domain by LanthaScreen TR-FRET competitive binding assay | Homo sapiens | 3 | ALA5226363 | single protein format | Scientific Literature | |
| 17. | ALA5229441 | B | Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown origin) assessed as recruitment of fluorescein-labeled PRIP/RAP250 coactivator peptide at 10 uM by LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 1 | ALA5226363 | single protein format | Scientific Literature | |
| 18. | ALA5229442 | B | Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown origin) assessed as recruitment of fluorescein-labeled SRC1 coactivator peptide by LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 1 | ALA5226363 | single protein format | Scientific Literature | |
| 19. | ALA5229443 | B | Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown origin) assessed as recruitment of fluorescein-labeled SRC3 coactivator peptide by LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 1 | ALA5226363 | single protein format | Scientific Literature | |
| 20. | ALA5229444 | B | Partial agonist activity at GST-tagged PPAR-gamma ligand binding domain (unknown origin) assessed as recruitment of fluorescein-labeled PRIP/RAP250 coactivator peptide by LanthaScreen TR-FRET Coactivator assay | Homo sapiens | 1 | ALA5226363 | single protein format | Scientific Literature |
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