# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2353002 | F | Antiproliferative activity against human MDA-MB-231 cells at 1 to 30 uM after 144 hrs by SRB assay | Homo sapiens | 3 | ALA2346643 | cell-based format | Scientific Literature | |
2. | ALA2353003 | F | Antiproliferative activity against human T47D cells at 1 to 30 uM after 144 hrs by SRB assay | Homo sapiens | 3 | ALA2346643 | cell-based format | Scientific Literature | |
3. | ALA2353008 | F | Antiproliferative activity against human T47D cells at 1 to 10 uM after 48 hrs by SRB assay | Homo sapiens | 11 | ALA2346643 | cell-based format | Scientific Literature | |
4. | ALA2353009 | F | Antiproliferative activity against human MDA-MB-231 cells at 1 to 10 uM after 48 hrs by SRB assay | Homo sapiens | 11 | ALA2346643 | cell-based format | Scientific Literature | |
5. | ALA2353015 | B | Inhibition of mitochondrial ETC complex 4 in human digitonin-permeabalized T47D cells assessed as inhibition of ascorbate/TMPD-initiated respiration at 10 uM after 2 hrs by Clarke-type electrode analysis in presence of antimycin A | Homo sapiens | 3 | ALA2346643 | cell-based format | Scientific Literature | |
6. | ALA2353018 | B | Inhibition of mitochondrial ETC complex 2 in human digitonin-permeabalized T47D cells assessed as inhibition of succinate-initiated respiration at 10 uM after 2 hrs by Clarke-type electrode analysis | Homo sapiens | 2 | ALA2346643 | cell-based format | Scientific Literature | |
7. | ALA2353019 | B | Inhibition of mitochondrial ETC complex 1 in human digitonin-permeabalized T47D cells assessed as inhibition of malate/pyruvate-initiated respiration at 10 uM after 2 hrs by Clarke-type electrode analysis | Homo sapiens | 2 | ALA2346643 | cell-based format | Scientific Literature | |
8. | ALA2353022 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of oxygen consumption at 10 uM after 2 hrs by Clarke-type electrode analysis | Homo sapiens | 4 | ALA2346643 | cell-based format | Scientific Literature | |
9. | ALA2353023 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of oxygen consumption at 10 uM after 10 mins by Clarke-type electrode analysis | Homo sapiens | 4 | ALA2346643 | cell-based format | Scientific Literature | |
10. | ALA2353024 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of oxygen consumption at 30 uM after 5 to 10 mins by Clarke-type electrode analysis | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature | |
11. | ALA2353250 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature | |
12. | ALA2353251 | B | Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA2346643 | cell-based format | Scientific Literature |