# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615512 | F | Effect on GLUT 1 glucose transporter expression in 3T3-L1 adipocytes at dose of 30 uM | Mus musculus | 4 | cell-based format | Scientific Literature | ||
2. | ALA631233 | P | Hydrophilicity was determined | 4 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA629144 | P | Partition coefficient (logP) | 13 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA635447 | P | Partition coefficient (logP) | 29 | assay format | Scientific Literature | |||
5. | ALA632264 | P | Dissociation constant measured by potentiometric titration (in duplicate) in 1:1 dioxane-water using a Fisher accumet pH meter model 630 and a Perkin-Elmer chart recorder model 56. | 13 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA875362 | P | Ionization constant for the compound | 4 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA647871 | B | in vitro aldose reductase inhibitory activity measured by NADPH-dependent inhibition of glyceraldehyde reduction in a partially purified bovine lens preparation at 10e -6M conc. | 1 | single protein format | Scientific Literature | |||
8. | ALA648019 | B | in vitro aldose reductase inhibitory activity measured by NADPH-dependent inhibition of glyceraldehyde reduction in a partially purified bovine lens preparation at 10e -7M conc.; g=no inhibitory activity | 1 | single protein format | Scientific Literature | |||
9. | ALA713388 | F | Hypoglycemic activity at dose 150 mg/Kg in KK-mice after peroral administration | Mus musculus | 15 | organism-based format | Scientific Literature | ||
10. | ALA717777 | F | Percent plasma glucose concentration of drug treated mice (ob/ob) relative to vehicle control animals | Mus musculus | 67 | organism-based format | Scientific Literature | ||
11. | ALA714392 | F | Antihyperglycemic activity was determined by measuring percent decrease in plasma glucose at 100 mg/kg/day | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA719038 | F | In vivo activity against hypocholesterol (CHOL) by using Alloxan-induced hyperlipoperoxidemia method in BALB/c mice after peroral administration at 100 mg/Kg dose | Mus musculus | 10 | organism-based format | Scientific Literature | ||
13. | ALA719043 | F | In vivo activity against serum lipid peroxidation level (s-LPO) by using Alloxan-induced hyperlipoperoxidemia method in BALB/c mice after peroral administration at 100 mg/Kg dose | Mus musculus | 10 | organism-based format | Scientific Literature | ||
14. | ALA716090 | F | In vivo activity against triglycerides (TG) by using Alloxan-induced hyperlipoperoxidemia method in BALB/c mice after peroral administration at 100 mg/Kg dose | Mus musculus | 10 | organism-based format | Scientific Literature | ||
15. | ALA719434 | F | percentage change in plasma glucose concentration of drug treated mice relative to vehicle controls at 100 mg/kg (once daily perorally x 4) in groups of db/db mice compared to vehicle control | Mus musculus | 8 | organism-based format | Scientific Literature | ||
16. | ALA723763 | F | Minimum effective dose for anti-hyperglycaemic activity was determined in C57B1/6 ob/ob obese mouse | Mus musculus | 8 | organism-based format | Scientific Literature | ||
17. | ALA723772 | F | Minimum effective dose required for significant reduction in blood glucose in ob/ob mice | Mus musculus | 8 | organism-based format | Scientific Literature | ||
18. | ALA724363 | F | Activity of perorally administered compound at a dose of 20 mg/kg for 10 days against plasma glucose in diabetic mice | Mus musculus | 3 | organism-based format | Scientific Literature | ||
19. | ALA724364 | F | Activity of perorally administered compound at a dose of 20 mg/kg for 4 days against plasma glucose in obese mice | Mus musculus | 15 | organism-based format | Scientific Literature | ||
20. | ALA724365 | F | Activity of perorally administered compound at a dose of 75 mg/kg for 4 days against plasma glucose in diabetic mice | Mus musculus | 3 | organism-based format | Scientific Literature |