#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2353183	B	Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric analysis	Homo sapiens	37		single protein format	Scientific Literature
2.	ALA2353184	B	Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric analysis	Homo sapiens	25		single protein format	Scientific Literature
3.	ALA2350602	A	Ratio of drug uptake in brain to plasma in C57B1/6NJ mouse at 30 mg/kg, po after 4 hrs by AlphaLISA	Mus musculus	3		organism-based format	Scientific Literature
4.	ALA2350611	P	Dissociation constant, pKa of the compound by capillary electrophoresis		16		small-molecule physicochemical format	Scientific Literature
5.	ALA2350616	F	Reduction of amyloid beta40 level in C57B1/6J mouse brain at 30 mg/kg, po after 4 hrs by AlphaLISA relative to control	Mus musculus	13		organism-based format	Scientific Literature
6.	ALA2350617	B	Selectivity ratio of IC50 for human BACE1 to IC50 for BACE1 in HEK293 cells	Homo sapiens	36		cell-based format	Scientific Literature
7.	ALA2350618	B	Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLISA technique	Homo sapiens	36		cell-based format	Scientific Literature
8.	ALA2404566	P	Lipophilicity, log D of the compound		3		small-molecule physicochemical format	Scientific Literature
9.	ALA2404567	P	Solubility of the compound by LYSA		2		small-molecule physicochemical format	Scientific Literature
10.	ALA2404569	A	Ratio of drug level in brain to plasma in wild-type C57Bl/6J mouse at 30 mg/kg, po after 4 hrs	Mus musculus	6		organism-based format	Scientific Literature
11.	ALA2404570	A	Drug uptake in wild-type C57Bl/6J mouse brain at 30 mg/kg, po after 4 hrs	Mus musculus	8		organism-based format	Scientific Literature
12.	ALA2404571	A	Plasma concentration in wild-type C57Bl/6J mouse at 30 mg/kg, po after 4 hrs	Mus musculus	8		organism-based format	Scientific Literature
13.	ALA2404575	P	Dissociation constant, pKa of the compound by capillary electrophoresis		24		small-molecule physicochemical format	Scientific Literature
14.	ALA2404722	F	Reduction in amyloid beta40 level in wild-type C57Bl/6J mouse brain at 30 mg/kg, po after 4 hrs	Mus musculus	9		organism-based format	Scientific Literature
15.	ALA2404723	A	Efflux ratio of permeability from basolateral to apical side over apical to basolateral side in pig LLC-PK1 cells transfected with human MDR1 after 3.5 hrs by LC-MS/MS analysis	Sus scrofa	24		cell-based format	Scientific Literature
16.	ALA2404724	B	Inhibition of BACE1 in HEK293 cells expressing wild type human APP assessed as reduction in amyloid beta40 level after 18 to 20 hrs by AlphaLISA	Homo sapiens	24		cell-based format	Scientific Literature
17.	ALA2404725	B	Inhibition of human BACE1 using MR121-labeled WSEVNLDAEFRC peptide as substrate incubated for 4 mins prior to substrate addition measured after 2 mins by fluorescence assay	Homo sapiens	25		single protein format	Scientific Literature
18.	ALA3705765	B	Inhitbition Assay: 48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of 96-hole half-area plate (a black plate: Costar), and after addition of 0.5 .mu.l of the test compound (dissolved in N,N'-dimethyl formaldehyde) and 1 .mu.l of Recombinant human BACE1(R&D Systems), the reaction mixture was incubated at 30.degree. C. for 3 hours. The substrate peptide was synthesized by reacting Cryptate TBPCOOH mono SMP (CIS bio international) with Biotin-XSEVNLDAEFRHDSGC (Peptide Institute, Inc.). The final concentrations of the substrate peptide and Recombinant human BACE1 were adjusted to 18 nmol/L and 7.4 nmol/L, respectively, and the reaction was performed in sodium acetate buffer (50 mmol/L sodium acetate, pH 5.0, 0.008% Triton X-100).After the incubation for reaction, 50 .mu.l of 8.0 .mu.g/ml Streptavidin-XL665 (CIS bio international) dissolved in phosphate buffer.	Homo sapiens	19		single protein format	BindingDB Database