# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2353183 | B | Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric analysis | Homo sapiens | 37 | single protein format | Scientific Literature | ||
2. | ALA2353184 | B | Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
3. | ALA2350615 | B | Selectivity ratio of IC50 for human BACE2 to IC50 for human BACE1 | Homo sapiens | 22 | assay format | Scientific Literature | ||
4. | ALA2350617 | B | Selectivity ratio of IC50 for human BACE1 to IC50 for BACE1 in HEK293 cells | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
5. | ALA2350618 | B | Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLISA technique | Homo sapiens | 36 | cell-based format | Scientific Literature |