| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2352098 | F | Induction of apoptosis in human K562 cells assessed as caspase-3/7 activation by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2352099 | F | Induction of apoptosis in human HCT116 cells assessed as caspase-3/7 activation up to 25 uM by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2352100 | F | Induction of apoptosis in human K562 cells assessed as PARP cleavage up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2352101 | F | Induction of apoptosis in human HCT116 cells assessed as PARP cleavage up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2352102 | F | Induction of apoptosis in human K562 cells assessed as decrease in MCL1 level after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2352103 | F | Induction of apoptosis in human HCT116 cells assessed as decrease in MCL1 level after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2352104 | F | Induction of apoptosis in human K562 cells assessed as caspase-3 activation up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2352105 | F | Induction of apoptosis in human K562 cells assessed as change in BCL2 level up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2352106 | F | Induction of apoptosis in human K562 cells assessed as change in PUMA level up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2352107 | F | Induction of apoptosis in human HCT116 cells assessed as caspase-3 activation up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2352108 | F | Induction of apoptosis in human HCT116 cells assessed as change in BCL2 level up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2352109 | F | Induction of apoptosis in human HCT116 cells assessed as change in PUMA level up to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2352110 | B | Inhibition of CDK9/CyclinT1 in human ARN8 cells assessed as increase in p53-dependent transcriptional activity at 2 uM after 24 hrs by beta-galactosidase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2352111 | B | Inhibition of CDK9/CyclinT1 in human ARN8 cells assessed as increase in p53-dependent transcriptional activity after 24 hrs by beta-galactosidase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2352112 | B | Inhibition of CDK9/CyclinT1 in human HCT116 cells assessed as decrease in Mdm2 expression at 1 to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2352113 | B | Inhibition of CDK9/CyclinT1 in human HCT116 cells assessed as increase in p21 expression at 1 to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2352114 | B | Inhibition of CDK9/CyclinT1 in human HCT116 cells assessed as increase in p53 expression at 1 to 5 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2352115 | B | Inhibition of CDK9/CyclinT1-mediated phosphorylation of RNA polymerase 2 at Ser5 in human K562 cells up to 25 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2352116 | B | Inhibition of CDK9/CyclinT1-mediated phosphorylation of RNA polymerase 2 at Ser2 in human K562 cells up to 25 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2352117 | B | Inhibition of CDK7/CyclinH/MAT1-mediated phosphorylation of RNA polymerase 2 at Ser5 in human K562 cells up to 25 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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