| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2350740 | F | Antiviral activity against R5 tropic HIV1 infected in human TZM-bl cells | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 2. | ALA2350741 | F | Antiviral activity against X4 tropic HIV1 BZ-167 infected in human TZM-bl cells assessed as neutralization of viral infectivity at 50 to 100 nM incubated 1 hr prior to viral infection measured after 72 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2350742 | F | Antiviral activity against X4 tropic HIV1 NL4-3 infected in human TZM-bl cells assessed as neutralization of viral infectivity at 50 to 100 nM incubated 1 hr prior to viral infection measured after 72 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2350743 | F | Antiviral activity against X4 tropic HIV1 isolate 92-UG-029 infected in human TZM-bl cells assessed as neutralization of viral infectivity at 50 to 100 nM incubated 1 hr prior to viral infection measured after 72 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2350744 | F | Antiviral activity against X4 tropic HIV1 isolate 92-HT-599 infected in human TZM-bl cells assessed as neutralization of viral infectivity at 50 to 100 nM incubated 1 hr prior to viral infection measured after 72 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2350745 | B | Inhibition of anti-CXCR4 mAb-44708 binding to CXCR4 in human H9 cells at 3 uM incubated for 20 mins prior to mAb-44708 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2351016 | B | Inhibition of anti-CXCR4 mAb-44717 binding to CXCR4 in human H9 cells at 3 uM incubated for 20 mins prior to mAb-44717 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2351017 | B | Inhibition of anti-CXCR4 mAb-12G5 binding to CXCR4 in human H9 cells at 3 uM incubated for 20 mins prior to mAbs-12G5 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA2351018 | B | Inhibition of anti-CXCR4 mAb-44716 binding to CXCR4 in human H9 cells at 3 uM incubated for 20 mins prior to mAbs-44716 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA2351019 | B | Inhibition of anti-CD4 mAb sim-2 binding to CD4 in PHA-induced human T cells at 0.1 to 10 uM incubated for 20 mins prior to mAb sim-2 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2351020 | B | Inhibition of anti-CD4 mAb sim-2 binding to CD4 in human H9 cells at 0.1 to 10 uM incubated for 20 mins prior to mAb sim-2 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2351021 | B | Inhibition of anti-CXCR4 mAb-12G5 binding to CXCR4 in PHA-induced human T cells at 0.1 to 10 uM incubated for 20 mins prior to mAbs-12G5 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2351022 | B | Inhibition of anti-CXCR4 mAb-12G5 binding to CXCR4 in human H9 cells at 0.1 to 10 uM incubated for 20 mins prior to mAbs-12G5 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA2351023 | B | Inhibition of anti-CXCR4 mAb-44716 binding to CXCR4 in human H9 cells at 1 uM incubated for 20 mins prior to mAbs-44716 addition measured after 1 hr by flow cytometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA2351024 | A | Cytotoxicity against PHA-induced human T cells up to 4 uM after 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2351025 | A | Cytotoxicity against human H9 cells up to 4 uM after 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2351026 | A | Cytotoxicity against human TZM-bl cells up to 4 uM after 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2351027 | A | Cytotoxicity against human MDA-MB-231 cells expressing CXCR4 after 48 to 72 hrs by MTS assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 19. | ALA2351028 | B | Inhibition of T-140 binding to CXCR4 (unknown origin) expressed in dog Cf2Th cells incubated for 30 mins prior to T-140 addition measured after 30 mins by fluorescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature |
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