# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3832817 | Functional | AntiToxoplasma gondii activity data Inhibition of plaque forming efficiency (%) Experiment A | Toxoplasma gondii | 15 | ALA3832761 | organism-based format | MMV Pathogen Box | |
2. | ALA3832818 | Functional | AntiToxoplasma gondii activity data Inhibition of plaque forming efficiency (%) Experiment B | Toxoplasma gondii | 6 | ALA3832761 | organism-based format | MMV Pathogen Box | |
3. | ALA3832819 | Functional | AntiToxoplasma gondii activity data 2-day killing assay: inhibition at 10 uM (%) Experiment C | Toxoplasma gondii | 15 | ALA3832761 | organism-based format | MMV Pathogen Box | |
4. | ALA3832820 | Functional | AntiToxoplasma gondii activity data 2-day killing assay: inhibition at 10 uM (%) Experiment D | Toxoplasma gondii | 15 | ALA3832761 | organism-based format | MMV Pathogen Box | |
5. | ALA3832821 | Functional | AntiToxoplasma gondii activity data 2-day killing assay: inhibition at 10 uM (%) Experiment E | Toxoplasma gondii | 15 | ALA3832761 | organism-based format | MMV Pathogen Box | |
6. | ALA3832822 | Functional | AntiToxoplasma gondii activity data 2-day killing assay: IC50 (uM), Experiment F | Toxoplasma gondii | 14 | ALA3832761 | organism-based format | MMV Pathogen Box | |
7. | ALA3832823 | Functional | AntiToxoplasma gondii activity data 2-day killing assay: IC50 (uM), Experiment G | Toxoplasma gondii | 9 | ALA3832761 | organism-based format | MMV Pathogen Box | |
8. | ALA3832839 | Functional | HL60 CC50 (uM) Cytotoxicity | 47 | ALA3832761 | cell-based format | MMV Pathogen Box | ||
9. | ALA2352559 | Functional | Antimalarial activity against chloroquine-resistant Plasmodium falciparum TM91C235 after 24 hrs by SYBR Green I based fluorescence assay | Plasmodium falciparum | 1 | ALA2346588 | organism-based format | Scientific Literature | |
10. | ALA2352560 | Functional | Antimalarial activity against Plasmodium falciparum D6 after 24 hrs by SYBR Green I based fluorescence assay | Plasmodium falciparum | 1 | ALA2346588 | organism-based format | Scientific Literature | |
11. | ALA2352561 | Toxicity | Toxicity in Toxoplasma gondii infected BALB/c mouse assessed mortality at 75 mg/kg, ip qd for 5 days measured 7 day after infection | Mus musculus | 1 | ALA2346588 | organism-based format | Scientific Literature | |
12. | ALA2352562 | Binding | Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP | Toxoplasma gondii | 7 | ALA2346588 | single protein format | Scientific Literature | |
13. | ALA2352563 | Functional | Antiparasitic activity against Toxoplasma gondii infected in BALB/c mouse assessed as reduction of parasite burden at 50 mg/kg, ip qd for 5 days | Toxoplasma gondii | 1 | ALA2346588 | organism-based format | Scientific Literature | |
14. | ALA2352564 | Functional | Antiparasitic activity against Toxoplasma gondii infected in BALB/c mouse assessed as reduction of parasite burden at 100 mg/kg, ip qd for 5 days | Toxoplasma gondii | 1 | ALA2346588 | organism-based format | Scientific Literature | |
15. | ALA2352565 | Binding | Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP at 1 uM | Toxoplasma gondii | 20 | ALA2346588 | single protein format | Scientific Literature | |
16. | ALA2352566 | ADME | Cytotoxicity against HFF assessed as inhibition of [3H]-thymidine incorporation after 24 hrs by WST-1 assay | Homo sapiens | 20 | ALA2346588 | cell-based format | Scientific Literature | |
17. | ALA2352567 | Functional | Antiparasitic activity against Toxoplasma gondii type 1 RH expressing YFP infected in HFF assessed as inhibition of [3H]-uracil incorporation after 72 hrs by liquid scintillation counting | Toxoplasma gondii | 19 | ALA2346588 | organism-based format | Scientific Literature | |
18. | ALA3987222 | Binding | Compound was evaluated for the inhibition of human FECH at 10uM | Homo sapiens | 400 | ALA3987221 | single protein format | MMV Pathogen Box | |
19. | ALA3987223 | Binding | Compound was evaluated for the inhibition of human HMBS at 100uM | Homo sapiens | 400 | ALA3987221 | assay format | MMV Pathogen Box | |
20. | ALA4296184 | Functional | Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020); MIC in CAMBH media, using NBS plates, by OD(600) | Staphylococcus aureus | 4,588 | ALA4296181 | organism-based format | CO-ADD antimicrobial screening data |