# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2353550 | B | Displacement of [3H]Ro15-1788 from recombinant GABA-A alpha5beta2gamma2 receptor benzodiazepine binding site (unknown origin) after 1 hr | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2353551 | B | Displacement of [3H]Ro15-1788 from recombinant GABA-A alpha2beta2gamma2 receptor benzodiazepine binding site (unknown origin) at 10 uM after 1 hr relative to control | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
3. | ALA2353552 | B | Displacement of [3H]Ro15-1788 from recombinant GABA-A alpha1beta2gamma2 receptor benzodiazepine binding site (unknown origin) after 1 hr | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
4. | ALA2353553 | F | Anticonvulsant activity in CD1 albino mouse assessed as protection against pentylenetetrazole-induced convulsions at 1 mg/kg, po administered 30 mins prior to pentylenetetrazole challenge measured over 30 mins (Rvb = 7.1%) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2353556 | T | Neurotoxicity in CD1 albino mouse assessed as decrease in number of falls from rotating rod at 10 mg/kg, po by rota-rod test relative to control | Mus musculus | 3 | organism-based format | Scientific Literature | ||
6. | ALA2353558 | F | Anxiolytic activity in CD1 albino mouse assessed as increase in time spent in illuminated side at 1 mg/kg, po administered 30 mins prior to testing measured for 5 mins by light-dark box test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2353567 | F | Procognitive effect in Harlan Wistar rat assessed as decrease in exploring time of unfamiliar rat during social investigatory behaviour at 0.3 to 10 mg/kg, po administered 30 mins prior to testing measured for 5 mins by social learning test relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2353571 | F | Procognitive effect in Harlan Wistar rat assessed as exploring time of familiar rat during social investigatory behaviour at 10 mg/kg, po administered 30 mins prior to testing measured for 5 mins by social learning test (Rvb = 27.6 secs) | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
9. | ALA2353818 | F | Procognitive effect in Harlan Wistar rat assessed as exploring time of familiar rat during social investigatory behaviour at 1 mg/kg, po administered 30 mins prior to testing measured for 5 mins by social learning test (Rvb = 27.6 secs) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA2353819 | F | Antiamnesic activity in CD1 albino mouse assessed as reversal of scopolamine-induced amnesia at 0.1 mg/kg, po administered 30 mins prior to scopolamine challenge measured after 24 hrs by passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA2353826 | F | Procognitive effect in Harlan Wistar rat assessed as exploring time of familiar rat during social investigatory behaviour at 0.3 mg/kg, po administered 30 mins prior to testing measured for 5 mins by social learning test (Rvb = 27.6 secs) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2353827 | F | Cognitive enhancing effect in CD1 albino mouse assessed as increase in retention latency at 0.1 to 10 mg/kg, po administered 30 mins prior to testing measured after 24 hrs by passive avoidance test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2351048 | B | Displacement of [3H]Ro15-1788 from GABA-A receptor benzodiazepine binding site in bovine cerebral cortex membranes after 1 hr | Bos taurus | 21 | cell membrane format | Scientific Literature |