| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2353874 | F | Selectivity ratio of EC50 for wild-type Toxoplasma gondii to EC50 for Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 2. | ALA2353875 | A | Cytotoxicity against African green monkey COS cells after 3 days by Alamar blue assay | Chlorocebus aethiops | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA2353876 | A | Cytotoxicity against CHO cells after 3 days by Alamar blue assay | Cricetulus griseus | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA2353877 | A | Cytotoxicity against human HEK293 cells after 3 days by Alamar blue assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA2353878 | A | Cytotoxicity against human HeLa cells after 3 days by Alamar blue assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA2353879 | F | Antiparasitic activity against transgenic Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 7. | ALA2353880 | F | Antiparasitic activity against wild-type Toxoplasma gondii expressing eukaryotic IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 8. | ALA2353881 | A | Half life in mouse liver microsomes by LC/MS/MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
| 9. | ALA2353882 | A | Half life in mouse liver microsomes by LC/MS/MS analysis in presence of NADPH | Mus musculus | 8 | microsome format | Scientific Literature | ||
| 10. | ALA2353885 | B | Inhibition of human IMPDH2 | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 11. | ALA2353886 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 12. | ALA2354115 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 13. | ALA3362091 | B | Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Bacillus anthracis | 17 | single protein format | Scientific Literature | ||
| 14. | ALA3362092 | B | Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Cryptosporidium | 17 | single protein format | Scientific Literature | ||
| 15. | ALA3362093 | B | Selectivity ratio of IC50 for Bacillus anthracis IMPDH to IC50 for Cryptosporidium IMPDH | 17 | assay format | Scientific Literature |
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