| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2353875 | A | Cytotoxicity against African green monkey COS cells after 3 days by Alamar blue assay | Chlorocebus aethiops | 6 | ALA2346559 | cell-based format | Scientific Literature | |
| 2. | ALA2353876 | A | Cytotoxicity against CHO cells after 3 days by Alamar blue assay | Cricetulus griseus | 6 | ALA2346559 | cell-based format | Scientific Literature | |
| 3. | ALA2353877 | A | Cytotoxicity against human HEK293 cells after 3 days by Alamar blue assay | Homo sapiens | 6 | ALA2346559 | cell-based format | Scientific Literature | |
| 4. | ALA2353878 | A | Cytotoxicity against human HeLa cells after 3 days by Alamar blue assay | Homo sapiens | 6 | ALA2346559 | cell-based format | Scientific Literature | |
| 5. | ALA2353881 | A | Half life in mouse liver microsomes by LC/MS/MS analysis | Mus musculus | 7 | ALA2346559 | microsome format | Scientific Literature | |
| 6. | ALA2353882 | A | Half life in mouse liver microsomes by LC/MS/MS analysis in presence of NADPH | Mus musculus | 8 | ALA2346559 | microsome format | Scientific Literature | |
| 7. | ALA2353885 | B | Inhibition of human IMPDH2 | Homo sapiens | 44 | ALA2346559 | single protein format | Scientific Literature | |
| 8. | ALA2353886 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA | Cryptosporidium parvum | 44 | ALA2346559 | assay format | Scientific Literature | |
| 9. | ALA2354115 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay | Cryptosporidium parvum | 44 | ALA2346559 | assay format | Scientific Literature | |
| 10. | ALA3362091 | B | Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Bacillus anthracis | 17 | ALA3351409 | single protein format | Scientific Literature | |
| 11. | ALA3362092 | B | Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Cryptosporidium | 17 | ALA3351409 | single protein format | Scientific Literature | |
| 12. | ALA3362093 | B | Selectivity ratio of IC50 for Bacillus anthracis IMPDH to IC50 for Cryptosporidium IMPDH | 17 | ALA3351409 | assay format | Scientific Literature | ||
| 13. | ALA4189875 | B | Inhibition of Mycobacterium tuberculosis IMPDH2deltaCBS mutant expressed in Escherichia coli BL21(DE3) cells using IMP as substrate by spectrophotometric method | Mycobacterium tuberculosis | 49 | ALA4184333 | cell-based format | Scientific Literature | |
| 14. | ALA4189876 | B | Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric method | Homo sapiens | 49 | ALA4184333 | single protein format | Scientific Literature | |
| 15. | ALA4189877 | B | Inhibition of human GMPR2 using GMP as substrate by spectrophotometric method | Homo sapiens | 49 | ALA4184333 | single protein format | Scientific Literature | |
| 16. | ALA4189878 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 17. | ALA4189879 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 18. | ALA4189880 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 19. | ALA4189881 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 20. | ALA4194981 | B | Inhibition of Mycobacterium tuberculosis GuaB2 expressed in Escherichia coli BL21(DE3) using [2-2H]-IMP or [2-1H]-IMP and NAD+ incubated for 2 hrs by 1H NMR method | Mycobacterium tuberculosis | 3 | ALA4190383 | assay format | Scientific Literature |
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