| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2353874 | F | Selectivity ratio of EC50 for wild-type Toxoplasma gondii to EC50 for Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | ALA2346559 | organism-based format | Scientific Literature | |
| 2. | ALA2353879 | F | Antiparasitic activity against transgenic Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | ALA2346559 | organism-based format | Scientific Literature | |
| 3. | ALA2353880 | F | Antiparasitic activity against wild-type Toxoplasma gondii expressing eukaryotic IMPDH | Toxoplasma gondii | 22 | ALA2346559 | organism-based format | Scientific Literature | |
| 4. | ALA2353881 | A | Half life in mouse liver microsomes by LC/MS/MS analysis | Mus musculus | 7 | ALA2346559 | microsome format | Scientific Literature | |
| 5. | ALA2353882 | A | Half life in mouse liver microsomes by LC/MS/MS analysis in presence of NADPH | Mus musculus | 8 | ALA2346559 | microsome format | Scientific Literature | |
| 6. | ALA2353885 | B | Inhibition of human IMPDH2 | Homo sapiens | 44 | ALA2346559 | single protein format | Scientific Literature | |
| 7. | ALA2353886 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA | Cryptosporidium parvum | 44 | ALA2346559 | assay format | Scientific Literature | |
| 8. | ALA2354115 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay | Cryptosporidium parvum | 44 | ALA2346559 | assay format | Scientific Literature | |
| 9. | ALA3362091 | B | Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Bacillus anthracis | 17 | ALA3351409 | single protein format | Scientific Literature | |
| 10. | ALA3362092 | B | Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | Cryptosporidium | 17 | ALA3351409 | single protein format | Scientific Literature | |
| 11. | ALA3362093 | B | Selectivity ratio of IC50 for Bacillus anthracis IMPDH to IC50 for Cryptosporidium IMPDH | 17 | ALA3351409 | assay format | Scientific Literature | ||
| 12. | ALA4189875 | B | Inhibition of Mycobacterium tuberculosis IMPDH2deltaCBS mutant expressed in Escherichia coli BL21(DE3) cells using IMP as substrate by spectrophotometric method | Mycobacterium tuberculosis | 49 | ALA4184333 | cell-based format | Scientific Literature | |
| 13. | ALA4189876 | B | Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric method | Homo sapiens | 49 | ALA4184333 | single protein format | Scientific Literature | |
| 14. | ALA4189877 | B | Inhibition of human GMPR2 using GMP as substrate by spectrophotometric method | Homo sapiens | 49 | ALA4184333 | single protein format | Scientific Literature | |
| 15. | ALA4189878 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 16. | ALA4189879 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 17. | ALA4189880 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 18. | ALA4189881 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | ALA4184333 | organism-based format | Scientific Literature | |
| 19. | ALA4355040 | B | Inhibition of Francisella tularensis IMPDH expressed in Escherichia coli BL21(DE3) deletion in guaB gene using IMP as substrate preincubated for 10 mins followed by substrate addition in presence of NAD by spectrophotometer | Francisella tularensis | 4 | ALA4354787 | assay format | Scientific Literature |
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