| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2353874 | F | Selectivity ratio of EC50 for wild-type Toxoplasma gondii to EC50 for Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 2. | ALA2353879 | F | Antiparasitic activity against transgenic Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 3. | ALA2353880 | F | Antiparasitic activity against wild-type Toxoplasma gondii expressing eukaryotic IMPDH | Toxoplasma gondii | 22 | organism-based format | Scientific Literature | ||
| 4. | ALA2353882 | A | Half life in mouse liver microsomes by LC/MS/MS analysis in presence of NADPH | Mus musculus | 8 | microsome format | Scientific Literature | ||
| 5. | ALA2353885 | B | Inhibition of human IMPDH2 | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 6. | ALA2353886 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 7. | ALA2354115 | B | Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 8. | ALA3362456 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature | ||
| 9. | ALA3362457 | B | Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Cryptosporidium | 6 | single protein format | Scientific Literature | ||
| 10. | ALA3362470 | B | Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Cryptosporidium | 2 | single protein format | Scientific Literature | ||
| 11. | ALA3362472 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature | ||
| 12. | ALA4355040 | B | Inhibition of Francisella tularensis IMPDH expressed in Escherichia coli BL21(DE3) deletion in guaB gene using IMP as substrate preincubated for 10 mins followed by substrate addition in presence of NAD by spectrophotometer | Francisella tularensis | 4 | assay format | Scientific Literature |
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