| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2352077 | F | Inhibition of PDGF-induced actin filament dissociation in human HASMC at 2 to 4 uM after 24 hrs by Rhodamine-Phalloidin staining based fluorescence microscopy | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 2. | ALA2352078 | A | Cytotoxicity against human HASMC assessed as effect on cell migration at 4 uM after 24 hrs by modified boyden chamber analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 3. | ALA2352079 | F | Inhibition of PDGF-induced human HASMC migration at 4 uM after 24 hrs by modified boyden chamber analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 4. | ALA2352080 | B | Inhibition of PDGFRbeta in human HASMC assessed as decrease in PDGF-induced ERK1/2 phosphorylation at 1 to 4 uM after 5 to 15 mins by Western blot analysis | Homo sapiens | 1 | ALA2346516 | single protein format | Scientific Literature | |
| 5. | ALA2352081 | B | Inhibition of PDGFRbeta in human HASMC assessed as decrease in PDGF-induced Akt phosphorylation at 1 to 4 uM after 5 to 15 mins by Western blot analysis | Homo sapiens | 1 | ALA2346516 | single protein format | Scientific Literature | |
| 6. | ALA2352082 | B | Inhibition of PDGFRbeta in human HASMC assessed as decrease in PDGF-induced PLC-gamma1 phosphorylation at 1 to 4 uM after 5 to 15 mins by Western blot analysis | Homo sapiens | 1 | ALA2346516 | single protein format | Scientific Literature | |
| 7. | ALA2352083 | B | Inhibition of PDGF-induced PDGFRbeta phosphorylation in human HASMC after 5 to 15 mins by Western blot analysis | Homo sapiens | 1 | ALA2346516 | single protein format | Scientific Literature | |
| 8. | ALA2352084 | F | Increase in p27 expression in PDGF-stimulated human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 9. | ALA2352085 | F | Increase in p21 expression in PDGF-stimulated human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 10. | ALA2352086 | F | Inhibition of PDGF-induced CDK4 expression in human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 11. | ALA2352350 | F | Inhibition of PDGF-induced cyclin D1 expression in human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 12. | ALA2352351 | F | Inhibition of PDGF-induced cyclin E expression in human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 13. | ALA2352352 | F | Inhibition of PDGF-induced CDK2 expression in human HASMC at 2 to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 14. | ALA2352353 | F | Cell cycle arrest in PGDF-stimulated human HASMC assessed as proportion of cells in S phase at 4 uM treated for 6 hrs prior to incubation with PDGF measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 20.8%) | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 15. | ALA2352354 | F | Cell cycle arrest in PGDF-stimulated human HASMC assessed as proportion of cells in S phase at 2 uM treated for 6 hrs prior to incubation with PDGF measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 20.8%) | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 16. | ALA2352355 | F | Cell cycle arrest in PGDF-stimulated human HASMC assessed as proportion of cells in S phase at 1 uM treated for 6 hrs prior to incubation with PDGF measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 20.8%) | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 17. | ALA2352356 | A | Cytotoxicity against human HASMC assessed as effect on cell vaibility at 0.5 to 4 uM after 24 hrs by MTT assay | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 18. | ALA2352357 | F | Inhibition of PDGF-induced human HASMC proliferation after 24 hrs by trypan blue dye exclusion assay | Homo sapiens | 1 | ALA2346516 | cell-based format | Scientific Literature | |
| 19. | ALA2352358 | F | Inhibition of PDGF-induced DNA synthesis in human HASMC assessed as decrease in [3H]thymidine incorporation after 20 hrs by microplate scintillation analysis | Homo sapiens | 6 | ALA2346516 | cell-based format | Scientific Literature |
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