# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2353168 | ADME | Hemolytic activity against human RBC at 12 uM after 30 mins relative to control | Homo sapiens | 3 | ALA2346628 | cell-based format | Scientific Literature | |
2. | ALA2353169 | ADME | Hemolytic activity against human RBC at 6 uM after 30 mins relative to control | Homo sapiens | 3 | ALA2346628 | cell-based format | Scientific Literature | |
3. | ALA2353172 | Functional | Membrane permeabilization effect on lysosome of human ECV304 cells assessed as induction of membrane lysis at 24 to 48 uM after 1 hr by N-Acetylglucosaminidase release assay | Homo sapiens | 1 | ALA2346628 | cell-based format | Scientific Literature | |
4. | ALA2353173 | Functional | Membrane permeabilization effect on lysosome of human ECV304 cells assessed as induction of membrane lysis up to 6 uM after 1 hr by N-Acetylglucosaminidase release assay | Homo sapiens | 5 | ALA2346628 | cell-based format | Scientific Literature | |
5. | ALA2353407 | Functional | Membrane permeabilization effect on human ECV304 cells assessed as increase in propidium iodide uptake at 12 uM after 1 hr by FACS flow cytometric analysis | Homo sapiens | 1 | ALA2346628 | cell-based format | Scientific Literature | |
6. | ALA2353410 | Functional | Membrane permeabilization effect on human ECV304 cells assessed as induction of membrane lysis at 48 uM after 1 hr | Homo sapiens | 3 | ALA2346628 | cell-based format | Scientific Literature | |
7. | ALA2353419 | Functional | Membrane permeabilization effect on human ECV304 cells assessed as normalized cell index at 12 to 24 uM measured every 15 secs for 3 hrs by real time impedance-based plate reader analysis relative to control relative to control | Homo sapiens | 1 | ALA2346628 | cell-based format | Scientific Literature | |
8. | ALA2353420 | Functional | Membrane permeabilization effect on human ECV304 cells assessed as normalized cell index at 6 uM measured every 15 secs for 3 hrs by real time impedance-based plate reader analysis relative to control | Homo sapiens | 1 | ALA2346628 | cell-based format | Scientific Literature | |
9. | ALA2353424 | Functional | Membrane permeabilization effect on human ECV304 cells at 3 uM measured every 15 secs for 3 hrs by real time impedance-based plate reader analysis | Homo sapiens | 2 | ALA2346628 | cell-based format | Scientific Literature |