| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2352849 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 400 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 2. | ALA2352850 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 200 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 3. | ALA2352851 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 100 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 4. | ALA2352852 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 50 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 5. | ALA2352853 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 25 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 6. | ALA2352854 | A | Free plasma concentration in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 7. | ALA2352855 | A | Free plasma concentration in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 8. | ALA2352856 | A | Free plasma concentration in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 9. | ALA2352857 | A | Free plasma concentration in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 10. | ALA2352863 | A | Free drug level in Sprague-Dawley rat brain at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 11. | ALA2352864 | A | Free drug level in Sprague-Dawley rat brain at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 12. | ALA2352865 | A | Free drug level in Sprague-Dawley rat brain at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 13. | ALA2352866 | A | Free drug level in Sprague-Dawley rat brain at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 14. | ALA2352872 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 15. | ALA2352873 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 16. | ALA2352874 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 17. | ALA2352875 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 18. | ALA2353100 | A | Drug uptake in Sprague-Dawley rat CSF at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 19. | ALA2353101 | A | Drug uptake in Sprague-Dawley rat CSF at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 20. | ALA2353102 | A | Drug uptake in Sprague-Dawley rat CSF at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!