#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2352848	F	Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control	Cavia porcellus	1	ALA2346596	organism-based format	Scientific Literature
2.	ALA2350204	A	Drug uptake in Hartley guinea pig CSF at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs	Cavia porcellus	1	ALA2346596	organism-based format	Scientific Literature
3.	ALA2351985	A	Free plasma concentration in Hartley guinea pig at 150 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs	Cavia porcellus	1	ALA2346596	organism-based format	Scientific Literature
4.	ALA2351991	A	Clearance in human liver microsomes at 1 uM after 20 mins by LC-MS/MS analysis in presence of NADPH	Homo sapiens	5	ALA2346596	microsome format	Scientific Literature
5.	ALA2351992	A	Clearance in cynomolgus monkey liver microsomes at 1 uM after 20 mins by LC-MS/MS analysis in presence of NADPH	Macaca fascicularis	5	ALA2346596	microsome format	Scientific Literature
6.	ALA2351993	A	Clearance in guinea pig liver microsomes at 1 uM after 20 mins by LC-MS/MS analysis in presence of NADPH	Cavia porcellus	5	ALA2346596	microsome format	Scientific Literature
7.	ALA2351994	A	Clearance in rat liver microsomes at 1 uM after 20 mins by LC-MS/MS analysis in presence of NADPH	Rattus norvegicus	5	ALA2346596	microsome format	Scientific Literature
8.	ALA2351995	A	Fraction unbound in guinea pig brain	Cavia porcellus	5	ALA2346596	tissue-based format	Scientific Literature
9.	ALA2351996	A	Fraction unbound in guinea pig plasma	Cavia porcellus	5	ALA2346596	cell-free format	Scientific Literature
10.	ALA2351997	A	Fraction unbound in rat brain	Rattus norvegicus	5	ALA2346596	tissue-based format	Scientific Literature
11.	ALA2351998	A	Fraction unbound in rat plasma	Rattus norvegicus	5	ALA2346596	cell-free format	Scientific Literature
12.	ALA2352010	A	Clearance in mouse liver microsomes at 1 uM after 20 mins by LC-MS/MS analysis in presence of NADPH	Mus musculus	13	ALA2346596	microsome format	Scientific Literature
13.	ALA2352013	A	Apparent permeability from apical to basolateral side in pig LLC-PK1 cells at 1 uM after 2 hrs by LC-MS/MS analysis	Sus scrofa	13	ALA2346596	cell-based format	Scientific Literature
14.	ALA2352014	A	Efflux ratio of permeability from basolateral to apical over apical to basolateral side in pig LLC-PK1 cells expressing human MDR1 at 1 uM after 2 hrs by LC-MS/MS analysis	Sus scrofa	59	ALA2346596	cell-based format	Scientific Literature
15.	ALA2352015	B	Inhibition of BACE1 in HEK293 cells expressing wild type APP assessed as level of amyloid beta (1 to 40) after 48 hrs by HTRF assay	Homo sapiens	59	ALA2346596	cell-based format	Scientific Literature
16.	ALA2352016	B	Selectivity ratio of IC50 for human spleen cathepsin D to IC50 for human recombinant BACE1	Homo sapiens	57	ALA2346596	tissue-based format	Scientific Literature
17.	ALA2352017	B	Inhibition of human spleen cathepsin D using 5-FAM/QXL as peptide substrate after 1 hr by FRET assay	Homo sapiens	59	ALA2346596	single protein format	Scientific Literature
18.	ALA2352293	B	Inhibition of human recombinant BACE1 expressed in CHO cells using biotin-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu peptide as substrate incubated for 15 mins prior to substrate addition measured after 2 hrs by HTRF assay	Homo sapiens	59	ALA2346596	cell-based format	Scientific Literature