| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2351361 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 12 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 2. | ALA2351362 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 3. | ALA2351363 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 4. | ALA2351364 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs relative to vehicle-treated control | Cavia porcellus | 2 | ALA2346596 | organism-based format | Scientific Literature | |
| 5. | ALA2351365 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 6. | ALA2351366 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 100 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 7. | ALA2351367 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 30 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 8. | ALA2351368 | F | Antialzheimer activity in Hartley guinea pig assessed as reduction in amyloid beta (1 to 40) level in CSF at 10 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs relative to vehicle-treated control | Cavia porcellus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 9. | ALA2352858 | A | Free plasma concentration in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 10. | ALA2352859 | A | Free plasma concentration in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 11. | ALA2352860 | A | Free plasma concentration in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 12. | ALA2352861 | A | Free plasma concentration in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 13. | ALA2352862 | A | Free plasma concentration in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 12 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 14. | ALA2352867 | A | Free drug level in Sprague-Dawley rat brain at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 15. | ALA2352868 | A | Free drug level in Sprague-Dawley rat brain at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 16. | ALA2352869 | A | Free drug level in Sprague-Dawley rat brain at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 5 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 17. | ALA2352870 | A | Free drug level in Sprague-Dawley rat brain at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 8 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 18. | ALA2352871 | A | Free drug level in Sprague-Dawley rat brain at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 12 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 19. | ALA2352876 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 1 hr | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature | |
| 20. | ALA2352877 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 60 mg/kg, po formulated with 1% CMC/0.5% Tween 80 after 3 hrs | Rattus norvegicus | 1 | ALA2346596 | organism-based format | Scientific Literature |
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