| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2354226 | F | PubChem BioAssay. HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set9. (Class of assay: confirmatory) | 21 | cell-based format | PubChem BioAssays | |||
| 2. | ALA2354239 | F | PubChem BioAssay. HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity_Set3. (Class of assay: confirmatory) | 26 | cell-based format | PubChem BioAssays | |||
| 3. | ALA2354300 | F | PubChem BioAssay. HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set10. (Class of assay: confirmatory) | 29 | cell-based format | PubChem BioAssays | |||
| 4. | ALA3406606 | B | Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid scintillation counting | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA3429061 | B | Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into cells by fluorescence assay | Mus musculus | 34 | cell-based format | Scientific Literature | ||
| 6. | ALA3429063 | P | Aqueous solubility in PBS buffer with 1% DMSO at 100 uM incubated for 24 hrs by UPLC-MS method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA3429064 | B | Reversible inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into cells by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3429065 | B | Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into cells pre-incubated for 2 hrs washed extensively with PBS and then incubated with DiI-HDL by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3429066 | B | Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation counting method | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3429067 | B | Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as increase in binding of Alexa-488-labeled HDL particles to cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3429068 | F | Inhibition of general receptor-mediated endocytosis in SR-BI isoform 1 expressing CHO cells assessed as effect on endocytosis of Alexa-594-labeled transferrin up to 35 uM | Cricetulus griseus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3429069 | A | Stability in human plasma assessed as compound remaining at 5 uM after 5 hrs at 37 degC by UPLC-MS method | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 13. | ALA3429070 | A | Stability in mouse plasma assessed as compound remaining at 5 uM after 5 hrs at 37 degC by UPLC-MS method | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 14. | ALA3429071 | A | Stability in human liver microsomes assessed as compound remaining at 1 uM in presence of NADPH at 37 degC after 1 hr by UHPLC-MS method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3429072 | A | Stability in mouse liver microsomes assessed as compound remaining at 1 uM in presence of NADPH at 37 degC after 1 hr by UHPLC-MS method | Mus musculus | 1 | assay format | Scientific Literature |
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