| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA739772 | F | In vivo effect on Tetrabenazine motor activity in mice following i.p. administration. | Mus musculus | 18 | ALA1125119 | organism-based format | Scientific Literature | |
| 2. | ALA739773 | F | In vivo effect on Tetrabenazine ptosis activity in mice following i.p. administration. | Mus musculus | 18 | ALA1125119 | organism-based format | Scientific Literature | |
| 3. | ALA739781 | F | Tested in vivo for head twitches antagonizing activity in mice | Mus musculus | 25 | ALA1125119 | organism-based format | Scientific Literature | |
| 4. | ALA740206 | B | Tested in vitro for dopamine(DA) neuronal uptake inhibition | 27 | ALA1125119 | single protein format | Scientific Literature | ||
| 5. | ALA740207 | B | Tested in vitro for norepinephrine (NE) neuronal uptake inhibition | 27 | ALA1125119 | single protein format | Scientific Literature | ||
| 6. | ALA740208 | B | Tested in vitro for serotonin(5-HT) neuronal uptake inhibition | 28 | ALA1125119 | single protein format | Scientific Literature | ||
| 7. | ALA779302 | F | In vitro inhibition of norepinephrine (NE) uptake in crude rat brain synaptosomes | Rattus norvegicus | 9 | ALA1123949 | organism-based format | Scientific Literature | |
| 8. | ALA872008 | F | In vitro inhibition of serotonin (5-HT) uptake in crude rat brain synaptosomes | Rattus norvegicus | 10 | ALA1123949 | organism-based format | Scientific Literature | |
| 9. | ALA783730 | F | Tested in vivo for serotonin syndrome antagonizing activity in rat | Rattus norvegicus | 9 | ALA1125119 | organism-based format | Scientific Literature | |
| 10. | ALA806926 | F | Percent inhibition of EtBr efflux against Staphylococcus aureus 1199B at 50 concentration | Staphylococcus aureus | 2 | ALA1146781 | organism-based format | Scientific Literature | |
| 11. | ALA847391 | F | Selectivity ratio measured as the ratio of IC50 of NE/IC50 of 5-HT | 10 | ALA1123949 | assay format | Scientific Literature | ||
| 12. | ALA1657423 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as reduction in ethidium bromide efflux at 50 uM by fluorimetry after 5 mins | Staphylococcus aureus | 112 | ALA1649083 | single protein format | Scientific Literature | |
| 13. | ALA3137722 | T | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 14. | ALA3137723 | T | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 15. | ALA3137724 | T | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is number of references indexed. [column 'AIGUE' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 16. | ALA3137725 | T | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 17. | ALA3137726 | T | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 18. | ALA3137727 | T | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 19. | ALA3137728 | T | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 20. | ALA3137729 | T | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature |
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