# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA708330 | Functional | Compound was tested for enhancement of proliferation of MCF-7 cell line at a concentration 1 uM | 22 | ALA1134138 | cell-based format | Scientific Literature | ||
2. | ALA708331 | Functional | Compound was tested for enhancement of proliferation of MCF-7 cell line at a concentration 10 uM | 22 | ALA1134138 | cell-based format | Scientific Literature | ||
3. | ALA708332 | Functional | Compound was tested for enhancement of proliferation of MCF-7 cell line at a concentration 3 uM | 20 | ALA1134138 | cell-based format | Scientific Literature | ||
4. | ALA1614211 | Functional | PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) | 36,499 | ALA1201862 | assay format | PubChem BioAssays | ||
5. | ALA1006486 | Functional | Cytotoxicity against MDR1 Pgp under-expressing human HCT116 cells after 24 hrs by MTT assay | Homo sapiens | 18 | ALA1156689 | cell-based format | Scientific Literature | |
6. | ALA1006487 | Functional | Cytotoxicity against MDR1 Pgp overexpressing human HepG2 cells after 24 hrs by MTT assay | Homo sapiens | 18 | ALA1156689 | cell-based format | Scientific Literature | |
7. | ALA3039488 | ADME | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | Cricetulus griseus | 1,862 | ALA3039007 | cell-based format | Scientific Literature | |
8. | ALA3039491 | ADME | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | Cricetulus griseus | 1,878 | ALA3039007 | cell-based format | Scientific Literature | |
9. | ALA3214913 | Binding | PubChem BioAssay. qHTS for Inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) | 4,591 | ALA1201862 | assay format | PubChem BioAssays | ||
10. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
11. | ALA4392938 | Binding | Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured soluble pig heart MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 20 to 40 mins by malachite green dye based spectrometric analysis relative to untreated control | Escherichia coli | 150 | ALA4392822 | assay format | Scientific Literature | |
12. | ALA4392939 | Binding | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis relative to untreated control | Escherichia coli | 150 | ALA4392822 | assay format | Scientific Literature | |
13. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
14. | ALA4495583 | Functional | SARS-CoV-2 3CL-Pro protease inhibition IC50 determined by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 109 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
15. | ALA4495584 | Functional | MERS_3CL Pro protease inhibition IC50 by FRET kind of response from peptide substrate | Middle East respiratory syndrome-related coronavirus | 80 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
16. | ALA4495585 | Functional | MERS 3CL-Pro protease inhibition percentage at 10 µM by FRET kind of response from peptide substrate | Middle East respiratory syndrome-related coronavirus | 70 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
17. | ALA4495586 | Functional | Chymotrypsin inhibition percentage at 10 µM by FRET kind of response from peptide substrate | Homo sapiens | 51 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
18. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |