# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA716350 | F | Antagonist activity against human Melanocortin 3 receptor at 10 uM | Homo sapiens | 13 | ALA1144940 | assay format | Scientific Literature | |
2. | ALA716360 | F | Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay. | 18 | ALA1144940 | assay format | Scientific Literature | ||
3. | ALA718190 | B | Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement. | 18 | ALA1144940 | single protein format | Scientific Literature | ||
4. | ALA878476 | F | Antagonist activity against human Melanocortin 4 receptor at 10 uM | Homo sapiens | 13 | ALA1144940 | assay format | Scientific Literature | |
5. | ALA709895 | F | Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay. | 18 | ALA1144940 | assay format | Scientific Literature | ||
6. | ALA714438 | B | Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement. | 18 | ALA1144940 | single protein format | Scientific Literature | ||
7. | ALA713027 | F | Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay. | 18 | ALA1144940 | assay format | Scientific Literature | ||
8. | ALA713000 | B | Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement. | 18 | ALA1144940 | single protein format | Scientific Literature | ||
9. | ALA5164333 | F | Agonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | ALA5154855 | cell-based format | Scientific Literature | |
10. | ALA5164334 | F | Agonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
11. | ALA5164336 | F | Agonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | ALA5154855 | cell-based format | Scientific Literature | |
12. | ALA5164337 | F | Agonist activity at human MC3R transfected in HEK293 cells assessed as cAMP accumulation by competitive binding assay | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
13. | ALA5164338 | F | Agonist activity at human MC4R transfected in HEK293 cells assessed as cAMP accumulation by competitive binding assay | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
14. | ALA5164339 | F | Agonist activity at human MC5R transfected in HEK293 cells assessed as cAMP accumulation by competitive binding assay | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
15. | ALA5164340 | F | Antagonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 10 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | ALA5154855 | cell-based format | Scientific Literature | |
16. | ALA5164341 | F | Antagonist activity at human MC3R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 30 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 3 | ALA5154855 | cell-based format | Scientific Literature | |
17. | ALA5164345 | F | Agonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
18. | ALA5164346 | F | Antagonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 70 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | ALA5154855 | cell-based format | Scientific Literature | |
19. | ALA5164353 | F | Agonist activity at human MC4R transfected in HEK293 cells assessed as cAMP accumulation | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature | |
20. | ALA5164354 | F | Agonist activity at human MC3R transfected in HEK293T cells co-transfected with GScAMP22F assessed as increase in cAMP level at 0.00001 to 10 uM by radioimmunoassay | Homo sapiens | 2 | ALA5154855 | cell-based format | Scientific Literature |