# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA640353 | Binding | Binding affinity against adenosine A1 receptor using N6-[3H]cyclohexyladenosine as radioligand in guinea pig forebrain membranes | Cavia porcellus | 46 | ALA1126169 | cell membrane format | Scientific Literature | |
2. | ALA645212 | Binding | Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligand | Cavia porcellus | 41 | ALA1125524 | cell membrane format | Scientific Literature | |
3. | ALA646320 | Binding | Binding affinity against adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide as radioligand in rat striatal membranes. | 37 | ALA1126169 | cell membrane format | Scientific Literature | ||
4. | ALA646483 | Binding | Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 50 nM cyclopentyladenosine | 41 | ALA1125524 | cell membrane format | Scientific Literature | ||
5. | ALA645334 | Binding | Selectivity is defined as the ratio of Ki(A2 adenosine receptor) / Ki(A1 adenosine receptor) | 32 | ALA1126169 | protein format | Scientific Literature | ||
6. | ALA849650 | Binding | Ratio of Ki at A2 receptor to that of A1 receptor | 37 | ALA1125524 | protein format | Scientific Literature | ||
7. | ALA791467 | Functional | Effect on urinary excretion potassium and sodium after oral administration of 1.6 mg/kg to rats(potassium and sodium excretion in control rat is 0.158+/-0.034) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
8. | ALA781748 | Functional | Serum creatinine concentration measured after intraperitoneal administration of 10 mg/kg of compound to rats(vehicle 4.26+/-0.39) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
9. | ALA780051 | Functional | Serum creatinine concentration measured after intraperitoneal administration of 1 mg/kg of compound to rats(vehicle 3.06+/-0.68) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
10. | ALA793847 | Functional | Ratio of urinary excretion value (Na+ concentration) in treated rats to that in control rats, at a peroral dose of 1.6 mg/Kg | Rattus norvegicus | 26 | ALA1125524 | organism-based format | Scientific Literature | |
11. | ALA793849 | Functional | Ratio of urinary excretion value (Na+ concentration) in treated rats to that in control rats, at a peroral dose of 25 mg/Kg | Rattus norvegicus | 26 | ALA1125524 | organism-based format | Scientific Literature | |
12. | ALA792710 | Functional | Ratio of urinary excretion value (urinary volume) in treated rats to that in control rats, at a peroral dose of 1.6 mg/Kg | Rattus norvegicus | 26 | ALA1125524 | organism-based format | Scientific Literature | |
13. | ALA792712 | Functional | Ratio of urinary excretion value (urinary volume) in treated rats to that in control rats, at a peroral dose of 25 mg/Kg | Rattus norvegicus | 26 | ALA1125524 | organism-based format | Scientific Literature | |
14. | ALA794914 | Functional | Urea nitrogen concentration measured after intraperitoneal administration of 10 mg/kg of compound to rats(vehicle 146.7+/-10.1) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
15. | ALA794923 | Functional | Urea nitrogen concentration measured after intraperitoneal administration of 1 mg/kg of compound to rats(vehicle 120.9+/-23.3) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
16. | ALA796379 | Functional | Oral diuretic activity was measured after oral administration of 1.6 mg/kg to rats(control volume is 1.12+/-0.33) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
17. | ALA794896 | Functional | Oral diuretic activity was measured after oral administration of 25 mg/kg to rats(control volume is 0.69+/-0.03) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
18. | ALA792406 | Functional | Percent inhibition of serum creatinine by the compound given as ratio of Cr value in treated to vehicle treated ones after intraperitoneal administration of 10 mg/kg of compound to rats(vehicle 4.26+/-0.39) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
19. | ALA792919 | Functional | Percent inhibition of serum creatinine by the compound given as ratio of Cr value in treated to vehicle treated ones after intraperitoneal administration of 1 mg/kg of compound to rats(vehicle 3.06+/-0.68) | Rattus norvegicus | 2 | ALA1125524 | organism-based format | Scientific Literature | |
20. | ALA795440 | Functional | Percent inhibition of serum creatinine by the compound given as ratio of UN value in treated to vehicle treated ones after intraperitoneal administration of 10 mg/kg of compound to rats(vehicle 146.7+/-10.1) | Rattus norvegicus | 1 | ALA1125524 | organism-based format | Scientific Literature |