# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2378321 | B | Binding affinity to human recombinant DAAO at 498 nm spectral modification by spectrophotometric analysis in presence of FAD | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2378322 | B | Binding affinity to human recombinant DAAO at 444 nm spectral modification by spectrophotometric analysis in presence of FAD | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA2378323 | B | Binding affinity to human recombinant DAAO at 395 nm spectral modification by spectrophotometric analysis in presence of FAD | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA2378324 | B | Binding affinity to human recombinant DAAO at 362 nm spectral modification by spectrophotometric analysis in presence of FAD | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA2378370 | F | Inhibition of DAAO in ip dosed Sprague-Dawley rat assessed as cerebellum concentration of compound required for 50% accumulation of D-serine after 6 hrs by LC/MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
6. | ALA2378378 | A | Drug uptake in C57BL/6 mouse cerebellum at 125 mg/kg, ip after 3 hrs by LC/MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2378379 | F | Inhibition of DAAO in C57BL/6 mouse assessed as increase in rate of D-serine accumulation in cerebellum at 125 mg/kg, ip by LC/MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2378382 | B | Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | Homo sapiens | 6 | single protein format | Scientific Literature | ||
9. | ALA2378383 | B | Competitive inhibition of human recombinant DAAO after 1 hr by coupled enzyme assay in presence of D-serine | Homo sapiens | 6 | single protein format | Scientific Literature | ||
10. | ALA2378384 | B | Binding affinity to human recombinant DAAO by stopped flow spectrophotometric analysis in presence of FAD | Homo sapiens | 6 | single protein format | Scientific Literature | ||
11. | ALA4376708 | A | Fraction unbound in Wistar Han rat plasma at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | cell-free format | Scientific Literature | ||
12. | ALA4376709 | A | Fraction unbound in Wistar Han rat white adipose tissue at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | tissue-based format | Scientific Literature | ||
13. | ALA4376710 | A | Fraction unbound in Wistar Han rat brain at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | tissue-based format | Scientific Literature | ||
14. | ALA4376711 | A | Fraction unbound in Wistar Han rat heart at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | tissue-based format | Scientific Literature | ||
15. | ALA4376712 | A | Fraction unbound in Wistar Han rat liver at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | tissue-based format | Scientific Literature | ||
16. | ALA4376713 | A | Fraction unbound in Wistar Han rat skeletal muscle at 2 uM incubated for 6 hrs by equilibrium dialysis method | Rattus norvegicus | 56 | tissue-based format | Scientific Literature | ||
17. | ALA4376714 | A | Total plasma concentration in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis | Rattus norvegicus | 56 | organism-based format | Scientific Literature | ||
18. | ALA4376715 | A | Drug concentration in total white adipose tissue in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis | Rattus norvegicus | 56 | organism-based format | Scientific Literature | ||
19. | ALA4376716 | A | Drug concentration in total brain in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis | Rattus norvegicus | 56 | organism-based format | Scientific Literature | ||
20. | ALA4376717 | A | Drug concentration in total heart in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis | Rattus norvegicus | 56 | organism-based format | Scientific Literature |