# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2378543 | B | Binding affinity to human ERG | Homo sapiens | 1 | ALA2375312 | single protein format | Scientific Literature | |
2. | ALA2378544 | A | Inhibition of human recombinant CYP2C9 | Homo sapiens | 1 | ALA2375312 | single protein format | Scientific Literature | |
3. | ALA2378545 | A | Inhibition of human recombinant CYP2D6 | Homo sapiens | 1 | ALA2375312 | single protein format | Scientific Literature | |
4. | ALA2378546 | A | Inhibition of human recombinant CYP3A4 | Homo sapiens | 1 | ALA2375312 | single protein format | Scientific Literature | |
5. | ALA2378547 | F | Inverse agonist activity at histamine H3 receptor in po dosed Swiss mouse assessed as release of N-tele-methylhistamine in brain after 90 mins by enzyme-immunoassay | Mus musculus | 2 | ALA2375312 | organism-based format | Scientific Literature | |
6. | ALA2378548 | F | Inverse agonist activity at histamine H3 receptor in po dosed Swiss mouse assessed as release of N-tele-methylhistamine in brain after 90 mins by enzyme-immunoassay relative to ciproxifan | Mus musculus | 1 | ALA2375312 | organism-based format | Scientific Literature | |
7. | ALA2378550 | A | AUC (0 to 8 hrs) in Swiss mouse plasma at 10 mg/kg, po by LS-MS/MS analysis | Mus musculus | 1 | ALA2375312 | organism-based format | Scientific Literature | |
8. | ALA2378551 | A | AUC (0 to 8 hrs) in Swiss mouse brain at 10 mg/kg, po by LS-MS/MS analysis | Mus musculus | 1 | ALA2375312 | organism-based format | Scientific Literature | |
9. | ALA2378560 | B | Displacement of [125I]-iodoproxyfan from histamine H3 receptor in mouse brain cortex after 1 hr by gamma counting analysis | Mus musculus | 22 | ALA2375312 | tissue-based format | Scientific Literature | |
10. | ALA2378561 | B | Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in HEK293 cells after 1 hr by gamma counting analysis | Homo sapiens | 22 | ALA2375312 | cell-based format | Scientific Literature |