# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2379687 | B | Selectivity ratio of IC50 for mouse recombinant P2X1 receptor to IC50 for human recombinant P2X3 receptor | 3 | assay format | Scientific Literature | |||
2. | ALA2379688 | B | Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium bromide uptake at 10 uM after 120 mins by fluorimetric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA2379689 | B | Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA2379814 | B | Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 20 mins prior to ATP-induction measured after compound washout by two-electrode voltage clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA2379815 | B | Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
6. | ALA2379816 | B | Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current at 100 nM incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA2379818 | B | Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current at 100 nM incubated for 20 mins prior to ATP-induction by two-electrode voltage clamp assay | Mus musculus | 7 | cell-based format | Scientific Literature |