| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2378506 | B | Selectivity ratio of IC50 for JAK2/1 to IC50 for JAK3/1 in human T cells expressing CD3 | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA2378507 | B | Selectivity ratio of IC50 for JAK2 in human monocytes expressing CD14 to IC50 for JAK3/1 in human T cells expressing CD3 | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA2378508 | B | Inhibition of JAK2/1 in human T cells expressing CD3 assessed as inhibition of IFNgamma-stimulated STAT1 phosphorylation | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA2378509 | B | Inhibition of JAK2 in human monocytes expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA2378510 | B | Inhibition of JAK3/1 in human T cells expressing CD3 assessed as inhibition of IL2-stimulated STAT5a phosphorylation | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA2378511 | P | Solubility of the compound by lyophilized solubility assay | 23 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA2378512 | B | Selectivity ratio of IC50 for JAK2 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 8. | ALA2378513 | B | Selectivity ratio of IC50 for JAK1 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 9. | ALA2378514 | B | Inhibition of JAK1 (unknown origin) using [33gammaP]ATP and Biotin-KAIETDKEYYTVKD as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by filtration assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 10. | ALA2378515 | B | Inhibition of JAK2 (unknown origin) using [33gammaP]ATP and Biotin-KAIETDKEYYTVKD as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by filtration assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 11. | ALA2378516 | B | Inhibition of JAK3 (unknown origin) using [33gammaP]ATP and Biotin-KAIETDKEYYTVKD as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by filtration assay | Homo sapiens | 23 | single protein format | Scientific Literature |
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