# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2378972 | B | Inhibition of JAK1/2 in human PBMC expressing CD14 assessed as inhibition of IFNgamma-induced STAT1 phosphorylation | Homo sapiens | 4 | protein complex format | Scientific Literature | ||
2. | ALA2378973 | B | Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-induced STAT5a phosphorylation | Homo sapiens | 4 | single protein format | Scientific Literature | ||
3. | ALA2378974 | B | Selectivity ratio of IC50 for JAK1 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 17 | assay format | Scientific Literature | ||
4. | ALA2378975 | B | Selectivity ratio of IC50 for JAK2 (unknown origin) to IC50 for JAK3 (unknown origin) | Homo sapiens | 17 | assay format | Scientific Literature | ||
5. | ALA2378976 | B | Inhibition of JAK1 (unknown origin) using Biotin-KAIETDKEYYTVKD as substrate and [33Pgamma]ATP incubated for 10 mins prior to substrate addition measured after 1 hr by Topcount analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
6. | ALA2378977 | B | Inhibition of JAK2 (unknown origin) expressed in SF21 cells using Biotin-KAIETDKEYYTVKD as substrate and [33Pgamma]ATP incubated for 10 mins prior to substrate addition measured after 30 mins by Topcount analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
7. | ALA2378978 | B | Inhibition of JAK3 (unknown origin) using Biotin-KAIETDKEYYTVKD as substrate and [33Pgamma]ATP incubated for 10 mins prior to substrate addition measured after 30 mins by Topcount analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
8. | ALA2378979 | B | Inhibition of JAK1/3 in human PBMC expressing CD3 assessed as inhibition of IL2-induced STAT5a phosphorylation | Homo sapiens | 4 | protein complex format | Scientific Literature |