# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2379071 | B | Agonist activity at GDH-tagged human TRPA1 receptor expressed in HEK293F cells assessed as increase in intracellular Ca2+ concentration by FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2379072 | B | Ratio of URB597 EC50 for human TRPA1 to compound EC50 for rat TRPA1 receptor | 1 | assay format | Scientific Literature | |||
3. | ALA2379073 | B | Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis | Rattus norvegicus | 32 | cell-based format | Scientific Literature | ||
4. | ALA2379074 | B | Agonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis relative to allyl isothiocyanate | Rattus norvegicus | 32 | cell-based format | Scientific Literature | ||
5. | ALA2379075 | B | Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ elevation incubated for 5 mins prior to capsaicin-stimulation by spectrofluorimetric analysis | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
6. | ALA2379076 | B | Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
7. | ALA2379077 | B | Agonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by spectrofluorimetric analysis relative to ionomycin | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
8. | ALA2379079 | B | Inhibition of MAGL (unknown origin) expressed in African green monkey COS7 cell cytosolic fraction assessed as [3H]2-AG hydrolysis to [3H]arachidonic acid after 20 mins by beta counting analysis | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
9. | ALA2379080 | B | Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis | Rattus norvegicus | 30 | cell membrane format | Scientific Literature | ||
10. | ALA2379081 | B | Antagonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular Ca2+ elevation incubated for 5 mins prior to allyl isothiocyanate-stimulation by spectrofluorimetric analysis | Rattus norvegicus | 32 | cell-based format | Scientific Literature |