# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2379709 | Binding | Inhibition of JNK3-mediated c-Jun phosphorylation in rat INS-1 cells after 3 hrs by ELISA | Rattus norvegicus | 4 | ALA2375283 | cell-based format | Scientific Literature | |
2. | ALA2379710 | ADME | Drug uptake in C57BL6 mouse brain at 10 mg/kg, ip after 2 hrs | Mus musculus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
3. | ALA2379711 | ADME | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg | Rattus norvegicus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
4. | ALA2379712 | ADME | Plasma concentration in C57BL6 mouse at 10 mg/kg, ip after 2 hrs | Mus musculus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
5. | ALA2379713 | ADME | AUC in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
6. | ALA2379714 | ADME | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
7. | ALA2379715 | ADME | Plasma clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 8 | ALA2375283 | organism-based format | Scientific Literature | |
8. | ALA2379717 | Binding | Inhibition of MAPK p38 (unknown origin)-mediated ATF2 Thr71 phosphorylation by HTRF assay | Homo sapiens | 7 | ALA2375283 | assay format | Scientific Literature | |
9. | ALA2379718 | Binding | Selectivity ratio of IC50 for JNK1 (unknown origin) to IC50 for JNK3 (unknown origin) | Homo sapiens | 26 | ALA2375283 | assay format | Scientific Literature | |
10. | ALA2379719 | Binding | Inhibition of JNK1 (unknown origin)-mediated ATF2 Thr71 phosphorylation by HTRF assay | Homo sapiens | 28 | ALA2375283 | single protein format | Scientific Literature | |
11. | ALA2379720 | Binding | Inhibition of JNK3 (unknown origin)-mediated ATF2 Thr71 phosphorylation by HTRF assay | Homo sapiens | 28 | ALA2375283 | single protein format | Scientific Literature |