# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2378869 | B | Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis incubated for 1 hr prior to RBC addition measured after 2 hrs by monocyte monolayer assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2378029 | F | Induction of apoptosis in human PBMC at 5 uM assessed as apoptotic index after 1 hr by Annexin V-APC/propidium iodide staining-based FACS analysis relative to IVIG | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA2378030 | B | Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis at 5 uM incubated for 1 hr prior to RBC addition measured after 2 hrs by monocyte monolayer assay relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
4. | ALA3265817 | P | Basic dissociation constant, pKa of the compound at 10 mM | 17 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA3265819 | P | Distribution coefficient, log D of the compound at 10 mM at pH 7.4 by pH-metric method | 17 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3265820 | F | Inhibition of human PBMC-induced phagocytosis of antibody-opsonized RBC at 5 uM incubated for 1 hr prior to RBC addition measured after 2 hrs by phase-contrast microscopy | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
7. | ALA3265822 | A | Induction of apoptosis in human PBMC assessed as apoptotic index at 10 uM after 1 hr by Annexin V/propidium iodide staining-based FACS analysis relative to IVIg | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
8. | ALA3265823 | A | Induction of apoptosis in human PBMC assessed as apoptotic index at 100 uM after 1 hr by Annexin V/propidium iodide staining-based FACS analysis relative to IVIg | Homo sapiens | 17 | cell-based format | Scientific Literature |