| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2378339 | ADME | Ratio of drug uptake in Wistar rat striatum after 2 mins to Wistar rat striatum after 30 mins | Rattus norvegicus | 27 | ALA2375274 | tissue-based format | Scientific Literature | |
| 2. | ALA2378340 | ADME | Ratio of drug uptake in Wistar rat brain to Wistar rat striatum after 30 mins | Rattus norvegicus | 27 | ALA2375274 | tissue-based format | Scientific Literature | |
| 3. | ALA2378341 | ADME | Biodistribution in Wistar rat brain after 30 mins | Rattus norvegicus | 27 | ALA2375274 | organism-based format | Scientific Literature | |
| 4. | ALA2378342 | Binding | Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenates | Rattus norvegicus | 39 | ALA2375274 | tissue-based format | Scientific Literature | |
| 5. | ALA2378343 | ADME | Biodistribution in Wistar rat whole brain after 2 mins | Rattus norvegicus | 26 | ALA2375274 | organism-based format | Scientific Literature | |
| 6. | ALA3889197 | Binding | In Vitro Potency Assay: The compounds were screened for their affinity for PBR using a method adapted from Le Fur et al (Life Sci. 1983; USA 33: 449-57).The compounds to be tested (dissolved in 50mM Tris-HCl, pH 7.4, 10 mM MgCl2 containing 1% DMSO) competed for binding to Wistar rat heart PBR against 0.3 nM [3H]-PK-11195. The reaction was carried out in 50 mM Tris-HCl, pH 7.4 10 mM MgCl2 for 15 minutes at 25° C. | Rattus norvegicus | 8 | ALA3886988 | single protein format | BindingDB Database |
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