| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2379198 | B | Inhibition of MAO-B in rat forebrain using [14C]PEA as substrate at 30 uM incubated for 20 mins prior to substrate addition measured after 10 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 2. | ALA2379199 | B | Inhibition of MAO-A in rat forebrain using [14C]5-HT as substrate at 30 uM incubated for 20 mins prior to substrate addition measured after 5 mins by liquid scintillation counting analysis relative to control | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA2379200 | A | Inhibition of human CYP3A4 assessed as terfenadine hydroxylation after 20 mins by LC/MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA2379201 | A | Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA2379202 | A | Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA2379432 | A | Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 7. | ALA2379435 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SR3637 infected in JCL/ICR mouse systemic infection model assessed as mortality administered as po measured over 7 days | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA2379436 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SR3637 infected in JCL/ICR mouse systemic infection model assessed as mortality administered as iv measured over 7 days | Staphylococcus aureus | 10 | organism-based format | Scientific Literature | ||
| 9. | ALA2379437 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus SR3637 assessed as growth inhibition by CLSI broth microdilution method | Staphylococcus aureus | 8 | organism-based format | Scientific Literature | ||
| 10. | ALA2379438 | F | Ratio of eperezolid MIC to compound MIC for Haemophilus influenzae SR27914 clinical isolate | Haemophilus influenzae | 6 | organism-based format | Scientific Literature | ||
| 11. | ALA2379439 | F | Ratio of eperezolid MIC to compound MIC for Streptococcus pneumoniae SR26207 clinical isolate | Streptococcus pneumoniae | 6 | organism-based format | Scientific Literature | ||
| 12. | ALA2379440 | F | Ratio of eperezolid MIC to compound MIC for Moraxella catarrhalis SR26840 clinical isolate | Moraxella catarrhalis | 6 | organism-based format | Scientific Literature | ||
| 13. | ALA2379441 | F | Ratio of eperezolid MIC to compound MIC for Enterococcus faecium SR7940 clinical isolate | Enterococcus faecium | 6 | organism-based format | Scientific Literature | ||
| 14. | ALA2379442 | F | Ratio of eperezolid MIC to compound MIC for Enterococcus faecalis SR1004 clinical isolate | Enterococcus faecalis | 6 | organism-based format | Scientific Literature | ||
| 15. | ALA2379443 | F | Ratio of eperezolid MIC to compound MIC for linezolid-resistant Staphylococcus aureus NRS271 | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA2379444 | F | Ratio of eperezolid MIC to compound MIC for Staphylococcus aureus Smith | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 17. | ALA2379445 | F | Ratio of eperezolid MIC to compound MIC for Staphylococcus aureus SR20549 clinical isolate | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
| 18. | ALA2379446 | F | Ratio of linezolid MIC to compound MIC for Moraxella catarrhalis SR26840 clinical isolate | Moraxella catarrhalis | 6 | organism-based format | Scientific Literature | ||
| 19. | ALA2379447 | F | Ratio of linezolid MIC to compound MIC for Streptococcus pneumoniae SR26207 clinical isolate | Streptococcus pneumoniae | 6 | organism-based format | Scientific Literature | ||
| 20. | ALA2379448 | F | Ratio of linezolid MIC to compound MIC for Haemophilus influenzae SR27914 clinical isolate | Haemophilus influenzae | 6 | organism-based format | Scientific Literature |
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