Genotoxicity in recombinant Salmonella typhimurium TA104 expressing Vibrio fisheri luxabcd genes under transcriptional control of recN2-4 promoter assessed as concentration required to cause DNA damage measured every 5 mins for 4 hrs by vitotox assay in presence of S9 fraction
Toxicity in recombinant Salmonella typhimurium TA104 expressing luxabcd genes under transcriptional control of constitutive pr1 promoter assessed as concentration required to reduce cell viability measured every 5 mins for 4 hrs by vitotox assay in presence of S9 fraction
Toxicity in recombinant Salmonella typhimurium TA104 expressing luxabcd genes under transcriptional control of constitutive pr1 promoter assessed as concentration required to reduce cell viability measured every 5 mins for 4 hrs by vitotox assay in absence of S9 fraction
Genotoxicity in recombinant Salmonella typhimurium TA104 expressing Vibrio fisheri luxabcd genes under transcriptional control of recN2-4 promoter assessed as concentration required to cause DNA damage measured every 5 mins for 4 hrs by vitotox assay in absence of S9 fraction
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in mouse J774.A1 cells at 1 MOI assessed as intracellular bacterial growth inhibition at 0.1 uM after 1 hr by luciferase reporter gene assay relative to control
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in mouse J774.A1 cells at 1 MOI assessed as intracellular bacterial growth inhibition at 1 uM after 1 hr by luciferase reporter gene assay relative to control
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in mouse J774.A1 cells at 1 MOI assessed as intracellular bacterial growth inhibition at 10 uM after 1 hr by luciferase reporter gene assay relative to control
Antimycobacterial activity against Mycobacterium avium subsp. paratuberculosis ATCC 19698 assessed as growth inhibition after 6 days by luciferase reporter gene assay
Antimycobacterial activity against Mycobacterium avium subsp. avium ATCC 15769 assessed as growth inhibition after 6 days by luciferase reporter gene assay
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition after 6 days by luciferase reporter gene assay
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition at 0.1 uM after 6 days by luciferase reporter gene assay relative to control
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition at 1 uM after 6 days by luciferase reporter gene assay relative to control