Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells compound preincubated for 1 hr measured after 48 hrs by prime/wash assay
Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells compound preincubated for 1 hr followed by wash out measured after 48 hrs by prime/wash assay
Ratio of EC50 for HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells with wash out to EC50 for HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells
Anti-HIV-1 activity against HIV1 BaL (subtype B, R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against laboratory adapted HIV1 IIIB (B, X4) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 91US_4(B, R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 00TZ_A125 (C, R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 BCF02 (O, R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 92UG024 (D, X4) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 BZ167/GS010 (B, X4) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 MN/H9 (A, X4) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 93/BR/020 (F, X4/R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against clinical isolate HIV1 97TH_NP1525 (CRF01_AE, X4/R5) assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA
Anti-HIV-1 activity against T20-sensitive HIV1 D36G assessed as inhibition of infection in human CEMx174 5.25M7 cells expressing CCR5/CXCR4 by measuring P24 antigen after 6 days by ELISA