# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2384407 | B | Inhibition of PDE11 (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
2. | ALA2384408 | B | Inhibition of PDE10A (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
3. | ALA2384409 | B | Inhibition of PDE8B (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
4. | ALA2384410 | B | Inhibition of PDE9A (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
5. | ALA2384411 | B | Inhibition of PDE7B (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
6. | ALA2384412 | B | Inhibition of PDE6A (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
7. | ALA2384413 | B | Inhibition of PDE5A (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
8. | ALA2384414 | B | Inhibition of PDE4D (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
9. | ALA2384415 | B | Inhibition of PDE3A (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
10. | ALA2384416 | B | Inhibition of PDE1B (unknown origin) | Homo sapiens | 1 | ALA2380216 | single protein format | Scientific Literature | |
11. | ALA2384417 | A | Ratio of free drug level in brain to plasma in Wistar Han rat at 1 mg/kg, iv after 2 hrs | Rattus norvegicus | 2 | ALA2380216 | organism-based format | Scientific Literature | |
12. | ALA2384418 | A | Ratio of total drug level in brain to plasma in Wistar Han rat at 1 mg/kg, iv after 2 hrs | Rattus norvegicus | 2 | ALA2380216 | organism-based format | Scientific Literature | |
13. | ALA2384419 | A | Fraction unbound in human plasma | Homo sapiens | 3 | ALA2380216 | cell-free format | Scientific Literature | |
14. | ALA2384420 | A | Fraction unbound in rat plasma | Rattus norvegicus | 3 | ALA2380216 | cell-free format | Scientific Literature | |
15. | ALA2384421 | A | Fraction unbound in rat brain | Rattus norvegicus | 3 | ALA2380216 | tissue-based format | Scientific Literature | |
16. | ALA2384422 | B | Inhibition of full length recombinant human PDE2A expressed in Sf21 cells using [3H]-cGMP as substrate by scintillation proximity assay | Homo sapiens | 7 | ALA2380216 | cell-based format | Scientific Literature | |
17. | ALA2384423 | A | Apparent permeability across apical to basolateral side in dog RRCK cells | Canis lupus familiaris | 3 | ALA2380216 | cell-based format | Scientific Literature | |
18. | ALA2384424 | A | Efflux ratio of apparent permeability across apical to basolateral side over basolateral to apical side in dog RRCK cells expressing MDR1 | Canis lupus familiaris | 3 | ALA2380216 | cell-based format | Scientific Literature | |
19. | ALA3705549 | B | Inhibition Assay: The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modified from the Amersham TRKQ7100 instructions (GE Healthcare, USA). | Homo sapiens | 84 | ALA3638950 | single protein format | BindingDB Database |