# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2382941 | A | AUC (0 to infinity) in Sprague-Dawley rat at 25 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2382942 | A | Oral bioavailability in Sprague-Dawley rat at 25 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
3. | ALA2382943 | A | Half life in Sprague-Dawley rat at 25 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2382944 | A | AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2382945 | A | Half life in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2382946 | A | Tmax in Sprague-Dawley rat at 25 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2382947 | A | Tmax in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2382948 | A | Cmax in Sprague-Dawley rat at 25 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2382949 | A | Cmax in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2382950 | F | Antimigratory activity against human MCF7 cells assessed as suppression of wound closure at 10 uM after 24 hrs by wound healing assay relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA2382951 | F | Antimigratory activity against human MCF7 cells assessed as suppression of wound closure at 5 uM after 24 hrs by wound healing assay relative to untreated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA2382952 | F | Antimigratory activity against human MCF7 cells after 24 hrs by Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA2382953 | F | Antimigratory activity against human MDA-MB-231 cells at 5 to 10 uM after 24 hrs by Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA2382954 | F | Cytotoxicity against ER-negative human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA2382955 | F | Cytotoxicity against ER-positive human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA2382956 | B | Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of MCAD expression after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA2382957 | B | Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of PDK4 expression after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA2382958 | F | Downregulation of ERRalpha expression in human MCF7 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA2382959 | B | Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of MCAD mRNA expression at 2.5 to 10 uM after 48 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA2382960 | B | Inhibition of ERRalpha in human MCF7 cells assessed as downregulation of PDK4 mRNA expression at 2.5 to 10 uM after 48 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |