| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2384212 | F | Inhibition of Eos influx in Black/6 mouse acute pulmonary cellular influx model at 1 mg/kg, po bid administered 1hr prior and 12 hrs post ova/alum challenge on day 28 and 29 relative to vehicle-treated control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2384213 | F | Inhibition of Eos influx in Black/6 mouse acute pulmonary cellular influx model at 1 mg/kg, po bid administered 1hr prior and 12 hrs post ova/alum challenge on day 28 and 29 relative to alpha4 antibody PS/2 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2384214 | B | Inhibition of integrin alpha5beta1 (unknown origin) binding to VCAM-1 in human THP1 cells after 30 mins by fibronectin mediated cell adhesion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2384215 | B | Inhibition of integrin alphaVbeta1 (unknown origin) binding to mouse OPN-HIS after 30 mins by fibronectin mediated cell adhesion assay | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 5. | ALA2384216 | B | Inhibition of integrin alphaLbeta2 (unknown origin) binding to VCAM-1 in human 8866 cells after 30 mins by fibronectin mediated cell adhesion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2384217 | B | Inhibition of integrin alpha4beta7 (unknown origin) binding to MadCAM in human 8866 cells after 30 mins by fibronectin mediated cell adhesion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2384218 | F | Antirheumatic activity in Lewis rat collagen induced arthritis model assessed as ankle histology at 3 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2384353 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as final paw weight at 3 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2384354 | F | Antirheumatic activity in Lewis rat collagen induced arthritis model assessed as ankle histology at 0.05 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2384355 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as final paw weight at 10 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2384356 | F | Antiinflammatory activity in guinea pig at 30 to 300 mg/kg, po bid for 12 days | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2384357 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as inhibition of AUC for ankle swelling at 3 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2384358 | F | Antiinflammatory activity in guinea pig at 30 mg/kg, po bid for 12 days every other day | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2384359 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as AUC for ankle swelling at 10 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2384360 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as bone resorbtion at 3 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2384361 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model assessed as cartilage destruction at 3 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA2384362 | F | Antiarthritic activity in Lewis rat collagen induced arthritis model at 3 to 30 mg/kg, po bid for 21 days | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA2384363 | F | Inhibition of Eos influx in Black/6 mouse acute pulmonary cellular influx model at 3 mg/kg, po bid administered 1hr prior and 12 hrs post ova/alum challenge on day 28 and 29 relative to vehicle-treated control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA2384364 | F | Inhibition of Eos influx in Black/6 mouse acute pulmonary cellular influx model at 3 mg/kg, po bid administered 1hr prior and 12 hrs post ova/alum challenge on day 28 and 29 relative to PS/2 | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA2384367 | B | Inhibition of VLA-4 in mouse serum binding to VCAM-1 in human Jurkat TM cells after 30 mins by fibronectin mediated cell adhesion assay | Mus musculus | 2 | cell-based format | Scientific Literature |
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