| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2384335 | A | Fraction unbound in rat plasma | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
| 2. | ALA2384337 | B | Inhibition of PARP3 (unknown origin) using histone as substrate after 1 hr by luminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2384338 | B | Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2384339 | A | AUCt in CD-1 mouse at 30 mg/kg, po | Mus musculus | 16 | organism-based format | Scientific Literature | ||
| 5. | ALA2384340 | A | Cmax in CD-1 mouse at 30 mg/kg, po | Mus musculus | 16 | organism-based format | Scientific Literature | ||
| 6. | ALA2384341 | A | Plasma protein binding in mouse | Mus musculus | 8 | cell-free format | Scientific Literature | ||
| 7. | ALA2384342 | A | Plasma protein binding in rat | Rattus norvegicus | 6 | cell-free format | Scientific Literature | ||
| 8. | ALA2384343 | A | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in pig LLC-PK1 cells expressing human MDR1 | Sus scrofa | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA2384344 | A | Apparent permeability of the compound across pig LLC-PK1 cells expressing human MDR1 | Sus scrofa | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA2384345 | P | Solubility of the compound in PBS at pH 7.4 | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA2384346 | P | Solubility of the compound in 0.01N HCl | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA2384347 | P | Solubility of the compound in simulated intestinal fluid at pH 6.8 | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA2384348 | A | Clearance in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2384349 | A | Half life in mouse plasma at 10 uM after 2 hrs by LC/MS/MS analysis | Mus musculus | 8 | cell-free format | Scientific Literature | ||
| 15. | ALA2384480 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 16. | ALA2384481 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 30 | microsome format | Scientific Literature | ||
| 17. | ALA2384482 | B | Inhibition of tankyrase in human SW480 cells assessed as degradation of beta catenin after 40 to 48 hrs | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 18. | ALA2384483 | B | Inhibition of tankyrase in human SW480 cells assessed as accumulation of axin2 after 24 hrs by Hoechst dye-based method | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 19. | ALA2384484 | B | Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 20. | ALA2384485 | B | Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assay | Homo sapiens | 5 | single protein format | Scientific Literature |
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