| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2384174 | P | Aqueous solubility of the compound in PBS buffer at pH 7.2 at 100 uM after 24 hrs | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA2384175 | A | Clearance in human liver microsomes at 1 uM up to 60 mins | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 3. | ALA2384176 | B | Inhibition of human recombinant carboxy-terminal his-tagged MDH-2 (20 to 338) expressed in Escherichia coli using oxaloacetic acid as substrate after 10 mins by UV endpoint analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA2384177 | B | Inhibition of human recombinant carboxy-terminal his-tagged MDH-1 (3 to 334) expressed in Escherichia coli using oxaloacetic acid as substrate after 10 mins by UV endpoint analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA2384178 | B | Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV endpoint analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 6. | ALA2384179 | B | Binding affinity to human recombinant carboxy-terminal avi-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis absence of NADH | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA2384180 | B | Binding affinity to human recombinant carboxy-terminal avi-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis presence of NADH | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 8. | ALA2384181 | B | Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate after 10 mins by MS endpoint analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA2384303 | B | Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate after 10 mins by UV endpoint analysis | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 10. | ALA3815700 | B | Inhibition of human carbonic anhydrase 1 preincubated for 6 hrs at 4 degC measured for 10 to 100 secs by stopped-flow carbon dioxide hydration assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 11. | ALA3815701 | B | Inhibition of human carbonic anhydrase 2 preincubated for 6 hrs at 4 degC measured for 10 to 100 secs by stopped-flow carbon dioxide hydration assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 12. | ALA3815702 | B | Inhibition of human carbonic anhydrase 9 catalytic domain preincubated for 6 hrs at 4 degC measured for 10 to 100 secs by stopped-flow carbon dioxide hydration assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 13. | ALA3815703 | B | Inhibition of human carbonic anhydrase 12 preincubated for 6 hrs at 4 degC measured for 10 to 100 secs by stopped-flow carbon dioxide hydration assay | Homo sapiens | 6 | single protein format | Scientific Literature |
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