| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2390449 | Binding | Inhibition of thromboxane A2 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | ALA2384997 | single protein format | Scientific Literature | |
| 2. | ALA2390450 | Binding | Inhibition of DP1 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | ALA2384997 | single protein format | Scientific Literature | |
| 3. | ALA2390622 | Binding | Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins followed by PGD2 addition measured after 4 mins by side scatter analysis | Homo sapiens | 5 | ALA2384997 | single protein format | Scientific Literature | |
| 4. | ALA2390624 | Functional | Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preincubated for 1 hr followed by 50 nM PGD2 and 0.1 nM [35S]-GTPgammaS addition measured after 2 hrs by liquid scintillation counting analysis | Homo sapiens | 34 | ALA2384997 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!