| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2390447 | F | Binding affinity to CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as dissociation half life at 10 X IC50 preincubated for 1 hr followed by 0.1 nM to 100 uM PGD2 and [35S]-GTPgammaS addition measured after 2 hrs by liquid scintillation counting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA2390449 | B | Inhibition of thromboxane A2 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 3. | ALA2390450 | B | Inhibition of DP1 receptor (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 4. | ALA2390622 | B | Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins followed by PGD2 addition measured after 4 mins by side scatter analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 5. | ALA2390624 | F | Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preincubated for 1 hr followed by 50 nM PGD2 and 0.1 nM [35S]-GTPgammaS addition measured after 2 hrs by liquid scintillation counting analysis | Homo sapiens | 34 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!