| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2388922 | F | Antagonist activity at dog CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Canis lupus familiaris | 27 | cell-based format | Scientific Literature | ||
| 2. | ALA2388923 | F | Antagonist activity at guinea pig CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Cavia porcellus | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA2388924 | F | Antagonist activity at rat CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Rattus norvegicus | 27 | cell-based format | Scientific Literature | ||
| 4. | ALA2388925 | F | Antagonist activity at mouse CRTH2 receptor assessed as inhibition of calcium flux by cell-based FLIPR assay | Mus musculus | 24 | cell-based format | Scientific Literature | ||
| 5. | ALA2388926 | A | Protein binding in plasma (unknown origin) | Not specified | 27 | cell-free format | Scientific Literature | ||
| 6. | ALA2388927 | B | Antagonist activity at ovine COX-1 | Ovis aries | 27 | single protein format | Scientific Literature | ||
| 7. | ALA2388928 | B | Antagonist activity at ovine COX-1 at 10 uM relative to control | Ovis aries | 27 | single protein format | Scientific Literature | ||
| 8. | ALA2388929 | F | Antagonist activity at human prostanoid TP2 receptor expressed in HEK293 cells assessed as inhibition of calcium flux after 30 to 40 mins by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 9. | ALA2388930 | B | Inhibition of beta-arrestin binding to recombinant human prostanoid EP2 receptor expressed in HEK293 cell membranes by beta-lactamase complementation assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 10. | ALA2388931 | B | Displacement of [3H]PGE2 from recombinant human prostanoid EP4 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysis | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 11. | ALA2388932 | B | Inhibition of beta-arrestin binding to recombinant human prostanoid EP4 receptor expressed in HEK293 cell membranes by beta-lactamase complementation assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 12. | ALA2388933 | F | Antagonist activity at human prostanoid EP3 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced calcium flux after 60 mins by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 13. | ALA2388934 | F | Antagonist activity at human prostanoid EP1 receptor expressed in CHOK1 cells assessed as inhibition of PGE2-induced calcium flux after 60 mins by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 14. | ALA2388935 | B | Selectivity factor, ratio of IC50 for recombinant human prostanoid DP1 receptor to IC50 for recombinant human CRTH2 receptor | Homo sapiens | 18 | assay format | Scientific Literature | ||
| 15. | ALA2388936 | B | Displacement of [3H]PGD2 from recombinant human prostanoid DP1 receptor expressed in CHO cells after 90 mins by scintillation counting analysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 16. | ALA2388937 | B | Antagonist activity at CRTH2 receptor in human eosinophils assessed as inhibition of PGD2-induced cell shape change incubated for 1 hr prior to PGD2 induction measured after 5 mins by FACS flow cytometric analysis in presence of human plasma | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 17. | ALA2388938 | F | Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2/forskolin-induced intracellular cAMP production after 20 mins by ELISA | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 18. | ALA2388939 | F | Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2-induced calcium flux after 5 mins by FLIPR assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 19. | ALA2388940 | B | Selectivity factor, ratio of IC50 for recombinant human CRTH2 receptor in presence of human serum albumin to IC50 for recombinant human CRTH2 receptor in absence of human serum albumin | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 20. | ALA2388941 | B | Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysis | Homo sapiens | 27 | cell-based format | Scientific Literature |
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